Sugi Predict

Sugi Predict / Compounds / SCHEMBL5503267

SCHEMBL5503267

SCHEMBL5503267

NC[C@H]1CCC[C@@H](C(=O)O)C1

nearest known ligand 0.57

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.57
▸ PLG P00747 1/20 0.57
▸ PLAT P00750 1/20 0.57
▸ ANPEP P15144 1/20 0.57
▸ GABRR1 P24046 5/20 0.43
▸ GABRR2 P28476 1/20 0.43
▸ CYP2D6 P10635 1/20 0.43
▸ PEPD P12955 1/20 0.42
▸ BTK Q06187 1/20 0.38
▸ GRM2 Q14416 1/20 0.38
▸ GRM3 Q14832 1/20 0.38
▸ SLC6A4 P31645 1/20 0.37
▸ SLC6A1 P30531 2/20 0.36
▸ SLC6A11 P48066 1/20 0.36
▸ TSHR P16473 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36
▸ SLC6A13 Q9NSD5 1/20 0.36
▸ CYP4F2 P78329 1/20 0.36
▸ CYP4A11 Q02928 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9504278 1.00 LMNA (0.57) LMNAPLGPLATANPEPGABRR1
SCHEMBL3282964 1.00 LMNA (0.57) LMNAPLGPLATANPEPGABRR1
SCHEMBL9504271 1.00 LMNA (0.57) LMNAPLGPLATANPEPGABRR1
SCHEMBL30484839 1.00 LMNA (0.57) LMNAPLGPLATANPEPGABRR1
SCHEMBL5503262 1.00 LMNA (0.57) LMNAPLGPLATANPEPGABRR1
SCHEMBL9294167 0.96 LMNA (0.57) LMNAPLGPLATANPEPGABRR1
SCHEMBL1965494 0.87 LMNA (0.75) LMNAPLGPLATANPEPGABRR1
SCHEMBL29954120 0.87 LMNA (0.75) LMNAPLGPLATANPEPGABRR1
SCHEMBL5722332 0.87 LMNA (0.75) LMNAPLGPLATANPEPGABRR1
SCHEMBL28816390 0.87 LMNA (0.75) LMNAPLGPLATANPEPGABRR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2024-12-05 — — US claimed
EP-0329105-B1 MOLECULAR WEIGHT CONTROLLER FOR POLYMERIZATION OF LACTAMS TO POLYAMIDES BASF Corporation (US) 1993-07-07 — — EP claimed
US-5006635-A Monofunctional amine, monofunctional acid, salt of aminoacid, polyamides BASF CORPORATION (US) 1991-04-09 — — US claimed
EP-0329105-A2 Molecular weight controller for polymerization of lactams to polyamides BASF Corporation (US) 1989-08-23 — — EP claimed
US-4844834-A Molecular weight controller for polymerization of lactams to polyamides BASF CORPORATION (US) 1989-07-04 — — US claimed
EP-3966226-B1 MASP INHIBITORY COMPOUNDS AND USES THEREOF BAYER AG (DE) 2025-12-24 — — EP disclosed
US-12503491-B2 MASP inhibitory compounds and uses thereof BAYER AKTIENGESELLSCHAFT (DE) 2025-12-23 — — US disclosed
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2024-12-05 — — US disclosed
US-20240124522-A1 MASP INHIBITORY COMPOUNDS AND USES THEREOF BAYER AKTIENGESELLSCHAFT (DE) 2024-04-18 — — US disclosed
US-20230303647-A1 CYCLIC CHEMERIN-9 DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 2023-09-28 — — US disclosed
EP-4196143-A1 CYCLIC CHEMERIN-9 DERIVATIVES Bayer Aktiengesellschaft (DE) 2023-06-21 — — EP disclosed
US-11667675-B2 MASP inhibitory compounds and uses thereof BAYER AKTIENGESELLSCHAFT (DE) 2023-06-06 — — US disclosed
WO-2022034057-A1 CYCLIC CHEMERIN-9 DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 2022-02-17 — — WO disclosed
US-20210246166-A1 MASP INHIBITORY COMPOUNDS AND USES THEREOF BAYER AKTIENGESELLSCHAFT (DE) 2021-08-12 — — US disclosed
EP-1799676-A2 NEW BICYCLIC ANTIBIOTICS Actelion Pharmaceuticals Ltd. (CH) 2007-06-27 — — EP disclosed
WO-2006032466-A2 NEW BICYCLIC ANTIBIOTICS ACTELION PHARMACEUTICALS LTD (CH) 2006-03-30 — — WO disclosed
EP-0329105-B1 MOLECULAR WEIGHT CONTROLLER FOR POLYMERIZATION OF LACTAMS TO POLYAMIDES BASF Corporation (US) 1993-07-07 — — EP disclosed
US-5006635-A Monofunctional amine, monofunctional acid, salt of aminoacid, polyamides BASF CORPORATION (US) 1991-04-09 — — US disclosed
EP-0329105-A2 Molecular weight controller for polymerization of lactams to polyamides BASF Corporation (US) 1989-08-23 — — EP disclosed
US-4844834-A Molecular weight controller for polymerization of lactams to polyamides BASF CORPORATION (US) 1989-07-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12503491-B2 MASP inhibitory compounds and uses thereof MASP2, SERPINB1, SPINT2 LMNA 984/4885PLG 88/4885PLAT 81/4885
US-20230303647-A1 CYCLIC CHEMERIN-9 DERIVATIVES CMKLR1, CMKLR2, CCL2 LMNA 2262/4885PLG 1204/4885PLAT 1537/4885
US-11667675-B2 MASP inhibitory compounds and uses thereof MASP2, SERPINB1, SPINT2 LMNA 984/4885PLG 88/4885PLAT 81/4885
US-20240124522-A1 MASP INHIBITORY COMPOUNDS AND USES THEREOF MASP2, SERPINB1, SPINT2 LMNA 984/4885PLG 88/4885PLAT 81/4885
US-20210246166-A1 MASP INHIBITORY COMPOUNDS AND USES THEREOF MASP2, SERPINB1, SPINT2 LMNA 984/4885PLG 88/4885PLAT 81/4885
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES BCAT1, BCAT2, PELP1 LMNA 4108/4885PLG 2099/4885PLAT 2945/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.