SCHEMBL1965494

SCHEMBL1965494

NCC1CCC(C(=O)O)C1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.75
PLG P00747 1/20 0.75
PLAT P00750 1/20 0.75
GABRR1 P24046 5/20 0.46
GABRR2 P28476 1/20 0.46
ANPEP P15144 2/20 0.44
ENPEP Q07075 1/20 0.44
ACE P12821 1/20 0.39
AKR1C3 P42330 1/20 0.38
AKR1C1 Q04828 1/20 0.38
CYP2D6 P10635 1/20 0.37
CYP1A2 P05177 2/20 0.37
ALOX15 P16050 2/20 0.37
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
GRM2 Q14416 2/20 0.36
GRM3 Q14832 2/20 0.36
GRM4 Q14833 2/20 0.36
F2 P00734 1/20 0.36
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29954120 1.00 LMNA (0.75) LMNAPLGPLATGABRR1GABRR2
SCHEMBL4350693 1.00 LMNA (0.75) LMNAPLGPLATGABRR1GABRR2
SCHEMBL28816390 1.00 LMNA (0.75) LMNAPLGPLATGABRR1GABRR2
SCHEMBL5722332 1.00 LMNA (0.75) LMNAPLGPLATGABRR1GABRR2
SCHEMBL5503267 0.87 LMNA (0.57) LMNAPLGPLATGABRR1GABRR2
SCHEMBL9294167 0.87 LMNA (0.57) LMNAPLGPLATGABRR1GABRR2
SCHEMBL9504278 0.87 LMNA (0.57) LMNAPLGPLATGABRR1GABRR2
SCHEMBL30484839 0.87 LMNA (0.57) LMNAPLGPLATGABRR1GABRR2
SCHEMBL5503262 0.87 LMNA (0.57) LMNAPLGPLATGABRR1GABRR2
SCHEMBL9504271 0.87 LMNA (0.57) LMNAPLGPLATGABRR1GABRR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4006080-A1 COMPOSITIONS, METHODS, AND ARTICLES RELATING TO IN-SITU CROSSLINKING OF POLYAMIDES DURING ADDITIVE MANUFACTURING Xerox Corporation (US) 2022-06-01 EP disclosed
US-20220010032-A1 PEPTIDE-NUCLEIC ACID COMPLEX KAWASAKI INSTITUTE OF INDUSTRIAL PROMOTION (JP) 2022-01-13 US disclosed
EP-2708569-B1 TRANSPARENT POLYAMIDE-IMIDES EMS PATENT AG (CH) 2018-05-23 EP disclosed
US-20170226159-A1 METHOD FOR PRODUCING HYDROPHOBIC PEPTIDE KANEKA CORPORATION (JP) 2017-08-10 US disclosed
US-9422429-B2 Transparent polyamide-imides EMS-PATENT AG (CH) 2016-08-23 US disclosed
US-20160222210-A1 TRANSPARENT POLYAMIDE-IMIDES EMS-PATENT AG (CH) 2016-08-04 US disclosed
CN-103665378-B Transparent polyamide-imide EMS PATENT AG (CH) 2016-01-20 CN disclosed
CN-103665378-A Transparent polyamide-imides EMS PATENT AG 2014-03-26 CN disclosed
EP-2708569-A1 Transparent polyamidimide EMS-PATENT AG (CH) 2014-03-19 EP disclosed
US-20140072745-A1 TRANSPARENT POLYAMIDE-IMIDES EMS-PATENT AG (CH) 2014-03-13 US disclosed
US-20030100576-A1 Methods and compounds for inhibiting mrp1 ELI LILLY AND COMPANY 2003-05-29 US disclosed
EP-1250340-A1 METHODS AND COMPOUNDS FOR INHIBITING MRP1 ELI LILLY AND COMPANY (US) 2002-10-23 EP disclosed
US-6410594-B1 VIRICIDES BIOCRYST PHARMACEUTICALS, INC. 2002-06-25 US disclosed
WO-2001046199-A1 METHODS AND COMPOUNDS FOR INHIBITING MRP1 ELI LILLY AND COMPANY (US) 2001-06-28 WO disclosed
EP-0933993-A1 SUBSTITUTED CYCLOPENTANE COMPOUNDS USEFUL AS NEURAMINIDASE INHIBITORS BIOCRYST PHARMACEUTICALS INC. (US) 1999-08-11 EP disclosed
WO-1997047194-A1 SUBSTITUTED CYCLOPENTANE COMPOUNDS USEFUL AS NEURAMINIDASE INHIBITORS BIOCRYST PHARMACEUTICALS, INC. (US) 1997-12-18 WO disclosed
EP-0329105-B1 MOLECULAR WEIGHT CONTROLLER FOR POLYMERIZATION OF LACTAMS TO POLYAMIDES BASF Corporation (US) 1993-07-07 EP disclosed
US-5006635-A Monofunctional amine, monofunctional acid, salt of aminoacid, polyamides BASF CORPORATION (US) 1991-04-09 US disclosed
EP-0329105-A2 Molecular weight controller for polymerization of lactams to polyamides BASF Corporation (US) 1989-08-23 EP disclosed
US-4844834-A Molecular weight controller for polymerization of lactams to polyamides BASF CORPORATION (US) 1989-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030100576-A1 Methods and compounds for inhibiting mrp1 ABCC1, ABCB11, ABCB1 LMNA 2226/4885PLG 2533/4885PLAT 2674/4885
US-20170226159-A1 METHOD FOR PRODUCING HYDROPHOBIC PEPTIDE VIP, HM13, HDGF LMNA 1444/4885PLG 84/4885PLAT 525/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.