Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 5/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.65 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.65 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.60 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.59 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.57 |
| ▸ | PPARG | P37231 | 7/20 | 0.57 |
| ▸ | PPARD | Q03181 | 7/20 | 0.57 |
| ▸ | PPARA | Q07869 | 7/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | TLR2 | O60603 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | FABP4 | P15090 | 2/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.57 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.57 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Octanedioate SCHEMBL28289307 | 0.97 | TSHR (0.71) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Glutarate SCHEMBL28290689 | 0.94 | SLC22A6 (0.69) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Adipic Acid SCHEMBL10764903 | 0.94 | LMNA (0.79) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Adipic Acid SCHEMBL5311340 | 0.94 | LMNA (0.79) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Adipic Acid SCHEMBL4353087 | 0.94 | LMNA (0.79) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Adipic Acid SCHEMBL11861116 | 0.91 | LMNA (0.65) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Adipic Acid SCHEMBL2538446 | 0.90 | LMNA (0.73) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Adipic Acid SCHEMBL258769 | 0.90 | LMNA (0.73) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Adipic Acid SCHEMBL8997800 | 0.90 | LMNA (0.73) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Adipic Acid SCHEMBL2791026 | 0.90 | LMNA (0.73) | LMNATSHRNFKB1PMP22AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999488-B | Single-component epoxy resin and preparation method thereof | 常州大学 | 2023-12-05 | — | — | CN | claimed |
| CN-111171285-B | Epoxy resin curing agent microcapsule taking polyurethane as shell material and preparation method thereof | 常州大学 | 2022-04-26 | — | — | CN | claimed |
| CN-113831495-A | Polyurethane material with controllable foaming time | 苏州意耐实业有限公司 | 2021-12-24 | — | — | CN | claimed |
| CN-113999488-B | Single-component epoxy resin and preparation method thereof | 常州大学 | 2023-12-05 | — | — | CN | disclosed |
| CN-113831495-A | Polyurethane material with controllable foaming time | 苏州意耐实业有限公司 | 2021-12-24 | — | — | CN | disclosed |
| CN-113831495-A | Polyurethane material with controllable foaming time | 苏州意耐实业有限公司 | 2021-12-24 | — | — | CN | disclosed |
| US-5330669-A | Polyurethane with phosphorus acid group | KYOWA HAKKO KOGYO CO., LTD. (US) | 1994-07-19 | — | — | US | disclosed |
| US-5292853-A | Magnetic recording media | KYOWA HAKKO KOGYO CO., LTD. (US) | 1994-03-08 | — | — | US | disclosed |
| US-5273826-A | Polyurethane containing phosphorus groups as binder | THE B. F. GOODRICH COMPANY (US) | 1993-12-28 | — | — | US | disclosed |
| EP-0377931-B1 | Isocyanate modified blocked sulfonic acid ester as a crosslinking catalyst | KING INDUSTRIES INC (US) | 1993-11-03 | — | — | EP | disclosed |
| US-5162162-A | Polyurethanes containing phosphorous compounds, epoxides and isocyanates; durability, wear resistance | THE B. F. GOODRICH COMPANY (US) | 1992-11-10 | — | — | US | disclosed |
| US-5158830-A | Magnetic recording medium comprising a polyurethane resin coating residual groups derived from specified phosphorous containing compounds | THE B. F. GOODRICH COMPANY (US) | 1992-10-27 | — | — | US | disclosed |
| US-5102961-A | Of hydroxyl, carboxyl or amide containing polymers; improved hardness, flexibility, adhesion and impact strength | KING INDUSTRIES (US) | 1992-04-07 | — | — | US | disclosed |
| US-5037934-A | Polyurethane resin binder from epoxy, isocyanates, phosphoric acid and polyhydroxy components; durability | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-08-06 | — | — | US | disclosed |
| EP-0377931-A2 | Isocyanate modified blocked sulfonic acid ester as a crosslinking catalyst | KING INDUSTRIES, INC. (US) | 1990-07-18 | — | — | EP | disclosed |
| EP-0367667-A2 | A new polyurethane resin containing at least one phosphoric acid group and its use in a magnetic coating formulation and a magnetic recording medium | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-05-09 | — | — | EP | disclosed |