Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 8/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.54 |
| ▸ | PDE4A | P27815 | 2/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.54 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9293623 | 1.00 | ADORA2B (0.63) | ADORA2BMAPK1RXFP1LMNASMN1; SMN2 | |
| SCHEMBL9295115 | 0.92 | ADORA2B (0.64) | ADORA2BMAPK1RXFP1LMNASMN1; SMN2 | |
| SCHEMBL9294238 | 0.91 | PDE4A (0.62) | ADORA2BMAPK1RXFP1LMNASMN1; SMN2 | |
| SCHEMBL6774762 | 0.89 | LMNA (0.71) | ADORA2BMAPK1RXFP1LMNASMN1; SMN2 | |
| SCHEMBL10811332 | 0.88 | LMNA (0.73) | ADORA2BMAPK1RXFP1LMNASMN1; SMN2 | |
| SCHEMBL8378780 | 0.87 | ADORA2B (0.56) | ADORA2BMAPK1RXFP1LMNASMN1; SMN2 | |
| SCHEMBL11701929 | 0.86 | ADORA2B (0.78) | ADORA2BMAPK1RXFP1LMNASMN1; SMN2 | |
| SCHEMBL11702145 | 0.86 | ADORA2B (0.78) | ADORA2BMAPK1RXFP1LMNASMN1; SMN2 | |
| SCHEMBL10394216 | 0.86 | ADORA2B (0.78) | ADORA2BMAPK1RXFP1LMNASMN1; SMN2 | |
| SCHEMBL11699832 | 0.86 | ADORA2B (0.78) | ADORA2BMAPK1RXFP1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5288721-A | Substituted epoxyalkyl xanthines | CELL THERAPEUTICS, INC. (US) | 1994-02-22 | — | — | US | disclosed |