Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL73240 | 0.86 | MAOB (0.45) | NPC1RAB9AMAOBKMT2AMEN1 | |
| SCHEMBL10786286 | 0.86 | MAOB (0.45) | NPC1RAB9AMAOBKMT2AMEN1 | |
| SCHEMBL12341996 | 0.80 | LMNA (0.52) | NPC1RAB9AMAOBKMT2AALDH1A1 | |
| SCHEMBL5204610 | 0.78 | RAB9A (0.53) | NPC1RAB9AKMT2AMAPTALDH1A1 | |
| SCHEMBL7345420 | 0.77 | LMNA (0.50) | NPC1RAB9AMAOBKMT2AMEN1 | |
| SCHEMBL6964456 | 0.77 | LMNA (0.50) | NPC1RAB9AMAOBKMT2AMEN1 | |
| SCHEMBL11713129 | 0.77 | RAB9A (0.52) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL11339158 | 0.76 | MAOB (0.44) | NPC1RAB9AMAOBKMT2AMEN1 | |
| SCHEMBL984344 | 0.76 | MAOB (0.62) | NPC1RAB9AMAOBMAPTALDH1A1 | |
| SCHEMBL8434039 | 0.76 | MAPT (0.49) | NPC1RAB9AMAOBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5281595-A | Pharmaceuticals | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1994-01-25 | — | — | US | disclosed |
| EP-0505005-A1 | Alkylenedioxyphenyl ether derivatives having anti-ischaemic, memory enhancing and anti-convulsive activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1992-09-23 | — | — | EP | disclosed |