SCHEMBL984344

SCHEMBL984344

CCOc1ccc2c(c1)OCO2

nearest known ligand 0.62

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAOB P27338 8/20 0.62
NPC1 O15118 1/20 0.61
RAB9A P51151 1/20 0.61
MAOA P21397 4/20 0.57
MAPT P10636 2/20 0.55
ALDH1A1 P00352 2/20 0.53
LMNA P02545 1/20 0.52
TSHR P16473 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
PDE5A O76074 1/20 0.52
MAPK1 P28482 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30627668 0.89 MAOB (0.62) MAOBNPC1RAB9AMAOAMAPT
SCHEMBL14088714 0.89 MAOB (0.62) MAOBNPC1RAB9AMAOAMAPT
SCHEMBL14539204 0.86 KCNH2 (0.57) MAOBMAPTALDH1A1TSHRSMN1; SMN2
SCHEMBL984460 0.85 MAOB (0.68) MAOBNPC1RAB9AMAOAMAPT
SCHEMBL984528 0.85 MAOB (0.68) MAOBNPC1RAB9AMAOAMAPT
SCHEMBL11695159 0.84 MAOB (0.69) MAOBNPC1RAB9AMAOAMAPT
SCHEMBL107322 0.84 MAOB (0.83) MAOBNPC1RAB9AMAOAMAPT
SCHEMBL11585486 0.83 MAOB (0.68) MAOBNPC1RAB9AMAOAMAPT
SCHEMBL108114 0.82 MAOB (0.74) MAOBNPC1RAB9AMAOAMAPT
SCHEMBL22221556 0.82 MAOB (0.64) MAOBNPC1RAB9AMAOAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105534785-B A kind of colouring compositions containing natural plant composition 肇庆迪彩日化科技有限公司 2018-11-02 CN claimed
US-11820862-B2 Organic fluorine compound, lubricant, and processing method of magnetic recording medium RESONAC CORPORATION (JP) 2023-11-21 US disclosed
WO-2022047375-A1 NOVEL FUNGAL MODULATORS TRUSTEES OF BOSTON UNIVERSITY (US) 2022-03-03 WO disclosed
US-20200131310-A1 ORGANIC FLUORINE COMPOUND, LUBRICANT, AND PROCESSING METHOD OF MAGNETIC RECORDING MEDIUM RESONAC CORPORATION (JP) 2020-04-30 US disclosed
CN-103327956-B Process for preparing hair colouring compositions 宝洁公司 2017-02-15 CN disclosed
EP-1957073-B1 MEDICINAL DRUG OTSUKA PHARMA CO LTD (JP) 2014-04-23 EP disclosed
US-8445501-B2 Substituted 7-carboxamido-pyrrolo[3,2-d]pyrimidines TAKEDA GMBH (DE) 2013-05-21 US disclosed
US-8293715-B2 10a-Azalide compound crosslinked at 10a- and 12-positions TAISHO PHARMACEUTICAL CO., LTD. (JP) 2012-10-23 US disclosed
US-20120238750-A1 AROMATIC COMPOUND OTSUKA PHARMACEUTICAL CO., LTD. 2012-09-20 US disclosed
US-20120238750-A1 AROMATIC COMPOUND OTSUKA PHARMACEUTICAL CO., LTD. 2012-09-20 US disclosed
WO-2009007399-A1 NEW COMPOUNDS AS HSP90 INHIBITORS CRYSTAX PHARMACEUTICALS, S.L. (ES) 2009-01-15 WO disclosed
US-20080306046-A1 Pyridyl Non-Aromatic Nitrogen-Containing Heterocyclic-1-Carboxylate Derivative FMC CORPORATION (US) 2008-12-11 US disclosed
WO-2008047883-A1 PIPERAZINE-SUBSTITUTED BENZOTHIOPHENES FOR TREATMENT OF MENTAL DISORDERS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2008-04-24 WO disclosed
US-7342115-B2 Binding antagonist and arylpyridine for antiinflammatory agents, cardiovascular disorders and antagonist or agonist and for immunology NEUROGEN CORPORATION (US) 2008-03-11 US disclosed
US-20070293667-A1 4-Amino-quinazolines MEDERSKI WERNER 2007-12-20 US disclosed
US-20070270422-A1 Aromatic Compounds OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-11-22 US disclosed
US-20070270422-A1 Aromatic Compounds OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-11-22 US disclosed
US-20070213330-A1 Anticancer agents; antiproliferative agents METHYLGENE INC. (CA) 2007-09-13 US disclosed
US-7253204-B2 Antiproliferative agents METHYLGENE INC. (CA) 2007-08-07 US disclosed
WO-2007066784-A2 DIARYLETHER DERIVATIVES AS ANTITUMOR AGENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-06-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070213330-A1 Anticancer agents; antiproliferative agents HDAC1, HDAC11, HDAC5 MAOB 3085/4885NPC1 1293/4885RAB9A 3036/4885
US-20120238750-A1 AROMATIC COMPOUND CBR1, CBR3, CYP1A1 MAOB 765/4885NPC1 1029/4885RAB9A 2782/4885
US-20080306046-A1 Pyridyl Non-Aromatic Nitrogen-Containing Heterocyclic-1-Carboxylate Derivative FAAH, FAAH2, APEH MAOB 156/4885NPC1 3724/4885RAB9A 2309/4885
US-20070270422-A1 Aromatic Compounds COL1A1, COL2A1, COL14A1 MAOB 402/4885NPC1 2588/4885RAB9A 3123/4885
US-20070293667-A1 4-Amino-quinazolines MRGPRX4, MRGPRX1, MRGPRX2 MAOB 3567/4885NPC1 1512/4885RAB9A 1097/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.