Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7746510 | 0.75 | KEAP1 (0.45) | KEAP1NFE2L2CYP2C19P2RY12PPARG | |
| SCHEMBL1976807 | 0.72 | GAA (0.52) | GAAMEN1KMT2AMAPTMCOLN3 | |
| SCHEMBL11282762 | 0.72 | HTR1D (0.32) | — | |
| SCHEMBL31226026 | 0.71 | ALDH1A1 (0.46) | KEAP1NFE2L2CYP2C19P2RY12PPARG | |
| SCHEMBL7838072 | 0.71 | PSMD10 (0.42) | KEAP1NFE2L2CYP2C19GAAKMT2A | |
| SCHEMBL9852204 | 0.70 | MEN1 (0.60) | CYP2C19PPARGGAAMEN1KMT2A | |
| SCHEMBL18179825 | 0.70 | MEN1 (0.60) | CYP2C19PPARGGAAMEN1KMT2A | |
| SCHEMBL4126086 | 0.70 | MEN1 (0.60) | CYP2C19PPARGGAAMEN1KMT2A | |
| SCHEMBL3386026 | 0.70 | KEAP1 (0.51) | KEAP1NFE2L2CYP2C19P2RY12GAA | |
| SCHEMBL3100559 | 0.70 | KEAP1 (0.51) | KEAP1NFE2L2CYP2C19P2RY12GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200317976-A1 | NOVEL PHASE CHANGE MATERIAL AND METHODS OF USE | MONASH UNIVERSITY (AU) | 2020-10-08 | — | — | US | claimed |
| EP-3458539-A1 | NOVEL PHASE CHANGE MATERIAL AND METHODS OF USE | Monash University (AU) | 2019-03-27 | — | — | EP | claimed |
| WO-2017197438-A1 | NOVEL PHASE CHANGE MATERIAL AND METHODS OF USE | MONASH UNIVERSITY (AU) | 2017-11-23 | — | — | WO | claimed |
| US-5326776-A | Tetrazoles | ABBOTT LABORATORIES (US) | 1994-07-05 | — | — | US | disclosed |
| WO-1993017681-A1 | ANGIOTENSIN II RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 1993-09-16 | — | — | WO | disclosed |