Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | VDR | P11473 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24682645 | 0.88 | CA1 (0.43) | KEAP1NFE2L2ALDH1A1KDM4EPTGS2 | |
| SCHEMBL9065972 | 0.86 | METAP1 (0.53) | ALDH1A1KDM4EPTGS2MAPTLMNA | |
| SCHEMBL10678288 | 0.85 | KEAP1 (0.40) | KEAP1NFE2L2ALDH1A1KDM4EPTGS2 | |
| SCHEMBL9937548 | 0.81 | KEAP1 (0.51) | KEAP1NFE2L2ALDH1A1KDM4EPTGS2 | |
| SCHEMBL8380811 | 0.80 | CA12 (0.45) | KEAP1NFE2L2ALDH1A1KDM4EPTGS2 | |
| SCHEMBL6607618 | 0.79 | GRM2 (0.42) | KEAP1NFE2L2ALDH1A1KDM4EPTGS2 | |
| SCHEMBL31090198 | 0.79 | CA12 (0.47) | KEAP1NFE2L2ALDH1A1LMNAMAPK1 | |
| SCHEMBL28242090 | 0.79 | KEAP1 (0.43) | KEAP1NFE2L2ALDH1A1PTGS2LMNA | |
| SCHEMBL29650620 | 0.79 | KEAP1 (0.43) | KEAP1NFE2L2ALDH1A1PTGS2LMNA | |
| SCHEMBL28424757 | 0.78 | MAPT (0.48) | ALDH1A1KDM4EMAPTLMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119462520-A | Preparation method of substituted benzoate derivative | 上海皓元医药股份有限公司 | 2025-02-18 | — | — | CN | claimed |
| EP-0011460-B1 | PEROXYGEN BLEACHING AND COMPOSITIONS THEREFOR | FMC Corporation (US) | 1982-09-29 | — | — | EP | claimed |
| EP-0011460-A1 | Peroxygen bleaching and compositions therefor | FMC Corporation (US) | 1980-05-28 | — | — | EP | claimed |
| CN-118666740-A | Synthesis of surface chiral [2.2] cyclopyridine/lactam compound by parallel kinetic resolution and preparation method thereof | 贵州大学 | 2024-09-20 | — | — | CN | disclosed |
| US-20230284521-A1 | LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING LIGHT-EMITTING DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2023-09-07 | — | — | US | disclosed |
| US-11725076-B2 | Polymer for formation of resist underlayer film, composition for formation of resist underlayer film comprising same and method for manufacturing semiconductor element by using same | SK INNOVATION CO., LTD. (KR) | 2023-08-15 | — | — | US | disclosed |
| CN-113788824-A | Pyridine compound | 第一三共株式会社 | 2021-12-14 | — | — | CN | disclosed |
| CN-110036007-B | Pyridine compound | 第一三共株式会社 | 2021-10-15 | — | — | CN | disclosed |
| US-20210163464-A1 | PYRIDINE COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2021-06-03 | — | — | US | disclosed |
| EP-3828178-A1 | PYRIDINE SALTS AND PROCESS | Daiichi Sankyo Company, Limited (JP) | 2021-06-02 | — | — | EP | disclosed |
| EP-3519398-B1 | PYRIDINE COMPOUND | DAIICHI SANKYO CO LTD (JP) | 2021-02-24 | — | — | EP | disclosed |
| US-6320017-B1 | POLYLACTONES FROM OMEGA-AMINO(OLIGOETHYLENE OXIDE)ALKANOIC ACID MONOMERS; CAN BE CONJUGATED TO LIPIDS, NUCLEIC ACIDS, PEPTIDES, PROTEINS, ETC. | INEX PHARMACEUTICALS CORP. (CA) | 2001-11-20 | — | — | US | disclosed |
| US-5098462-A | Herbicides | SANDOZ LTD. (CH) | 1992-03-24 | — | — | US | disclosed |
| US-5098466-A | Herbicides | SANDOZ LTD. (CH) | 1992-03-24 | — | — | US | disclosed |
| EP-0219451-B1 | SEMICARBAZONES AND THIOSEMICARBAZONES | SANDOZ AG (CH) | 1991-03-20 | — | — | EP | disclosed |
| EP-0258182-A1 | Semicarbazones and thiosemicarbazones | SANDOZ AG (CH) | 1988-03-02 | — | — | EP | disclosed |
| EP-0219451-A1 | Semicarbazones and thiosemicarbazones | SANDOZ AG (CH) | 1987-04-22 | — | — | EP | disclosed |
| EP-0011460-B1 | PEROXYGEN BLEACHING AND COMPOSITIONS THEREFOR | FMC Corporation (US) | 1982-09-29 | — | — | EP | disclosed |
| US-4215003-A | INCLUDING HETEROCYCLIC SULFONATE ESTERS OF AN ALKANE- OR ARYLSULFONIC ACID AS ACTIVATORS; LOW TEMPERATURE | FMC CORPORATION (US) | 1980-07-29 | — | — | US | disclosed |
| EP-0011460-A1 | Peroxygen bleaching and compositions therefor | FMC Corporation (US) | 1980-05-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210163464-A1 | PYRIDINE COMPOUND | RET, ABL1, ROS1 | KEAP1 702/4885NFE2L2 2093/4885ALDH1A1 1589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.