Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11844301 | 0.75 | MEN1 (0.41) | GAALMNARAB9AMAPTKMT2A | |
| SCHEMBL12749333 | 0.74 | EDNRA (0.41) | GAAALDH1A1GRM1KMT2ANPC1 | |
| SCHEMBL6287846 | 0.74 | EDNRA (0.41) | GAAALDH1A1GRM1KMT2ANPC1 | |
| SCHEMBL7423767 | 0.65 | HCRTR1 (0.44) | GAAALDH1A1KMT2ANPC1TDP1 | |
| SCHEMBL1844609 | 0.64 | NPC1 (0.48) | KMT2ANPC1TDP1MEN1 | |
| SCHEMBL22830919 | 0.64 | AKR1C3 (0.43) | TAAR1GAALMNARAB9AMAPT | |
| SCHEMBL22830852 | 0.64 | AKR1C3 (0.43) | TAAR1GAALMNARAB9AMAPT | |
| SCHEMBL22492144 | 0.64 | AKR1C3 (0.43) | TAAR1GAALMNARAB9AMAPT | |
| SCHEMBL29599708 | 0.64 | AKR1C3 (0.43) | TAAR1GAALMNARAB9AMAPT | |
| SCHEMBL21400400 | 0.64 | ALDH1A1 (0.33) | ALDH1A1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276053-A | Dibenzothiopyranylamines | WARNER-LAMBERT COMPANY (US) | 1994-01-04 | — | — | US | disclosed |