Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9563646 | 0.87 | CHRM2 (0.44) | CYP2C19CPT1BCHRM2OPRK1CYP1A2 | |
| SCHEMBL9563644 | 0.73 | CPT1B (0.47) | CYP2C19CPT1BCHRM2OPRK1CYP1A2 | |
| SCHEMBL8541237 | 0.68 | CYP2C19 (0.43) | CYP2C19CPT1BCHRM2OPRK1CYP1A2 | |
| SCHEMBL9297113 | 0.65 | CHRM2 (0.45) | CYP2C19CPT1BCHRM2OPRK1CYP1A2 | |
| SCHEMBL28298203 | 0.62 | CHRM2 (0.79) | CYP2C19CHRM2OPRK1CYP1A2SLC6A4 | |
| SCHEMBL9622246 | 0.62 | USP2 (0.45) | CYP2C19MEN1KMT2ALMNAADORA3 | |
| SCHEMBL10346385 | 0.62 | CHRM2 (0.45) | CYP2C19CPT1BCHRM2OPRK1CYP1A2 | |
| SCHEMBL10346640 | 0.62 | CYP2C19 (0.50) | CYP2C19CHRM2OPRK1CYP1A2SLC6A4 | |
| SCHEMBL10346941 | 0.61 | CYP2C19 (0.53) | CYP2C19CHRM2OPRK1CYP1A2SLC6A4 | |
| SCHEMBL20595548 | 0.60 | CHRM2 (0.70) | CYP2C19CHRM2OPRK1CYP1A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5283246-A | Trimetazidine compounds | ADIR ET COMPAGNIE (FR) | 1994-02-01 | — | — | US | disclosed |