Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9296206 | 0.87 | CYP2C19 (0.36) | CHRM2OPRK1LMNAHTTADORA3 | |
| SCHEMBL9563644 | 0.80 | CPT1B (0.47) | CHRM2OPRK1LMNAHTTADORA3 | |
| SCHEMBL8541237 | 0.75 | CYP2C19 (0.43) | CHRM2OPRK1LMNAHTTADORA3 | |
| SCHEMBL9297113 | 0.72 | CHRM2 (0.45) | CHRM2OPRK1LMNAHTTADORA3 | |
| SCHEMBL28298203 | 0.69 | CHRM2 (0.79) | CHRM2OPRK1LMNAHTTADORA3 | |
| SCHEMBL30591064 | 0.68 | CHRM2 (0.64) | CHRM2OPRK1LMNAHTTADORA3 | |
| SCHEMBL21173512 | 0.68 | CHRM2 (0.67) | CHRM2OPRK1LMNAHTTADORA3 | |
| SCHEMBL10346385 | 0.68 | CHRM2 (0.45) | CHRM2OPRK1LMNAHTTADORA3 | |
| SCHEMBL10346640 | 0.68 | CYP2C19 (0.50) | CHRM2OPRK1LMNAHTTCYP2C19 | |
| SCHEMBL10346941 | 0.67 | CYP2C19 (0.53) | CHRM2OPRK1HTTCYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533579-A1 | Trimetazidine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-03-24 | — | — | EP | disclosed |