Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | NT5E | P21589 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.42 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9095566 | 0.93 | NPC1 (0.53) | NPBWR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9296252 | 0.88 | NT5E (0.60) | SLC2A1NT5ENPBWR1HPSEMEN1 | |
| SCHEMBL31289528 | 0.87 | MEN1 (0.54) | NT5EXDHHPSEMEN1KMT2A | |
| SCHEMBL18656067 | 0.81 | MAPT (0.55) | XDHMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL9095571 | 0.81 | NPC1 (0.56) | SLC2A1NT5ENPBWR1MEN1KMT2A | |
| SCHEMBL23800775 | 0.79 | XDH (0.50) | XDHMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL20178503 | 0.79 | LMNA (0.53) | XDHMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL9295726 | 0.77 | MPL (0.57) | SLC2A1NT5ENPBWR1NPC1RAB9A | |
| SCHEMBL14684214 | 0.76 | NT5E (0.61) | NT5ENPBWR1HPSEMEN1KMT2A | |
| SCHEMBL18656068 | 0.76 | KDM4E (0.41) | XDHKMT2ANPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581955-A1 | USE OF BENZIMIDAZOLE DERIVATIVES AS PROTECTIVE LIGHT FILTERS. | MERCK PATENT GMBH (DE) | 1994-02-09 | — | — | EP | disclosed |
| WO-1993015712-A1 | USE OF BENZIMIDAZOLE DERIVATIVES AS PROTECTIVE LIGHT FILTERS | MERCK PATENT GMBH (DE) | 1993-08-19 | — | — | WO | disclosed |