Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.38 |
| ▸ | WNT3A | P56704 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 8/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzofuran SCHEMBL5860505 | 0.89 | MAOA (0.39) | CTNNB1WNT3AMAOAMAOBFTO | |
| Benzofuran SCHEMBL9735995 | 0.89 | MAOA (0.41) | LOXL2CTNNB1WNT3AMAOAMAOB | |
| Benzofuran SCHEMBL7085367 | 0.87 | CTNNB1 (0.41) | CTNNB1WNT3AMAOAMAOBFTO | |
| Benzofuran SCHEMBL27880879 | 0.86 | MAOA (0.40) | CTNNB1WNT3AMAOAMAOBFTO | |
| Benzofuran SCHEMBL3160534 | 0.86 | — | — | |
| Benzofuran SCHEMBL29415475 | 0.86 | — | — | |
| Benzofuran SCHEMBL5834531 | 0.86 | MAOA (0.46) | CTNNB1WNT3AMAOAMAOBFTO | |
| Benzofuran SCHEMBL5564 | 0.86 | — | — | |
| Benzofuran SCHEMBL29393518 | 0.86 | — | — | |
| Benzofuran SCHEMBL29006510 | 0.85 | MEN1 (0.39) | CTNNB1WNT3AMAOAMAOBFTO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5308866-A | Treatment of melatonin related disorders, sleep disorders, psychological disorders | ADIR ET COMPAGNIE (FR) | 1994-05-03 | — | — | US | disclosed |