SCHEMBL92968

SCHEMBL92968

OCc1cc(Cl)ccc1Cl

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.48
HIF1A Q16665 3/20 0.48
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
MAPT P10636 2/20 0.48
IDO1 P14902 2/20 0.48
HPGD P15428 2/20 0.48
ALOX15 P16050 2/20 0.48
SLC22A1 O15245 1/20 0.48
USP2 O75604 1/20 0.48
LMNA P02545 1/20 0.48
HSP90AA1 P07900 1/20 0.48
HSPD1 P10809 1/20 0.48
HSPA5 P11021 1/20 0.48
ALOX12 P18054 1/20 0.48
CASP1 P29466 1/20 0.48
HTT P42858 1/20 0.48
BLM P54132 1/20 0.48
HSPE1 P61604 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1154758 0.82 IDO1 (0.50) CYP3A4HIF1AMEN1KMT2AMAPT
SCHEMBL29493203 0.82 IDO1 (0.50) CYP3A4HIF1AMEN1KMT2AMAPT
SCHEMBL1560923 0.81 CYP3A4 (0.45) CYP3A4HIF1AMEN1KMT2AMAPT
Dichlorobenzyl Alcohol SCHEMBL29433936 0.80 IDO1 (0.60) CYP3A4IDO1LMNAHTTSMN1; SMN2
Dichlorobenzyl Alcohol SCHEMBL41323 0.80 IDO1 (0.60) CYP3A4IDO1LMNAHTTSMN1; SMN2
Dichlorobenzyl Alcohol SCHEMBL8519503 0.78 IDO1 (0.58) CYP3A4IDO1LMNAHTTSMN1; SMN2
SCHEMBL31621229 0.78 RECQL (0.43) IDO1HPGDSMN1; SMN2TSHRSLC6A4
SCHEMBL31515787 0.78 HIF1A (0.71) CYP3A4HIF1AMEN1KMT2AMAPT
SCHEMBL29825244 0.78 MAPT (0.50) CYP3A4HIF1AMEN1KMT2AMAPT
SCHEMBL696050 0.78 HSD17B10 (0.54) CYP3A4MEN1KMT2AMAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 274 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12559582-B2 Polyacrylate polymer BASF SE (DE) 2026-02-24 US claimed
CN-117964834-A Polyacrylate polymers 巴斯夫欧洲公司 2024-05-03 CN claimed
US-6989052-B1 Phase change ink printing process XEROX CORPORATION (US) 2006-01-24 US claimed
US-20060004123-A1 PHASE CHANGE INK PRINTING PROCESS XEROX CORPORATION 2006-01-05 US claimed
US-12559582-B2 Polyacrylate polymer BASF SE (DE) 2026-02-24 US disclosed
CN-117964834-A Polyacrylate polymers 巴斯夫欧洲公司 2024-05-03 CN disclosed
EP-4289838-A2 ARYLMETHOXY ISOINDOLINE DERIVATIVES AND COMPOSITIONS COMPRISING AND METHODS OF USING THE SAME Celgene Corporation (US) 2023-12-13 EP disclosed
EP-3599236-B1 ARYLMETHOXY ISOINDOLINE DERIVATIVES AND COMPOSITIONS COMPRISING AND METHODS OF USING THE SAME CELGENE CORP (US) 2023-08-23 EP disclosed
US-11718791-B2 Polymerisable compounds and the use thereof in liquid-crystal displays MERCK PATENT GMBH (DE) 2023-08-08 US disclosed
EP-3755764-B1 POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2023-05-10 EP disclosed
US-20220411402-A1 ARYLMETHOXY ISOINDOLINE DERIVATIVES AND COMPOSITIONS COMPRISING AND METHODS OF USING THE SAME CELGENE CORPORATION 2022-12-29 US disclosed
US-11414399-B2 Arylmethoxy isoindoline derivatives and compositions comprising and methods of using the same CELGENE CORPORATION (US) 2022-08-16 US disclosed
EP-0713703-A2 Substituted phenylpyrimidine derivatives, useful in the treatment or prevention of CNS disorders THE WELLCOME FOUNDATION LIMITED (GB) 1996-05-29 EP disclosed
US-5136080-A Intermediates for glutamate inhibitors BURROUGHS WELLCOME CO. (US) 1992-08-04 US disclosed
EP-0372934-A2 Pharmacologically active CNS compounds THE WELLCOME FOUNDATION LIMITED (GB) 1990-06-13 EP disclosed
EP-0198687-A2 Alpha-polyhaloketoximes ROHM AND HAAS COMPANY (US) 1986-10-22 EP disclosed
US-4554111-A α-Hydroxyethylphosphinates, and their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-11-19 US disclosed
US-4544652-A α-Hydroxyethylphosphinates, and their use as fungicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-10-01 US disclosed
EP-0093010-A2 Alpha-hydroxyethylphosphinates, and their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-11-02 EP disclosed
US-4040977-A HALOACETAMIDE OR THIOCYANOACETAMIDE-ALCOHOL-FORMALDEHYDE CONDENSATES STERLING DRUG INC. (US) 1977-08-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11718791-B2 Polymerisable compounds and the use thereof in liquid-crystal displays VCL, ILK, LCP1 CYP3A4 1699/4885HIF1A 4862/4885MEN1 2071/4885
US-12559582-B2 Polyacrylate polymer SAAL1, ATXN2L, VCL CYP3A4 1944/4885HIF1A 1324/4885MEN1 3341/4885
US-20220411402-A1 ARYLMETHOXY ISOINDOLINE DERIVATIVES AND COMPOSITIONS COMPRISING AND METHODS OF USING THE SAME CYP3A7, CYP3A4, CYP3A43 CYP3A4 2/4885HIF1A 4194/4885MEN1 3301/4885
US-11414399-B2 Arylmethoxy isoindoline derivatives and compositions comprising and methods of using the same CYP3A7, CYP3A4, CYP3A43 CYP3A4 2/4885HIF1A 4194/4885MEN1 3301/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.