Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL92947 | 0.89 | CA2 (0.33) | CA2CA1ALDH1A1KMT2AATM | |
| SCHEMBL23802513 | 0.86 | CA2 (0.43) | CA2CA1ALDH1A1KMT2AATM | |
| SCHEMBL8654311 | 0.84 | ALDH1A1 (0.36) | CA2CA1ALDH1A1PKMKMT2A | |
| SCHEMBL13441949 | 0.84 | LMNA (0.39) | CA2CA1ALDH1A1PKMKMT2A | |
| SCHEMBL12275897 | 0.84 | SMN1; SMN2 (0.36) | CA2ALDH1A1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL18540023 | 0.83 | CA2 (0.53) | CA2CA1ALDH1A1ATMMAPK1 | |
| SCHEMBL19820110 | 0.83 | CA2 (0.41) | CA2CA1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL19404107 | 0.83 | CA2 (0.41) | CA2CA1ALDH1A1KMT2AMAPK1 | |
| SCHEMBL20624810 | 0.82 | CA2 (0.44) | CA2CA1ALDH1A1KMT2AMAPK1 | |
| SCHEMBL24674795 | 0.82 | CA2 (0.44) | CA2CA1ALDH1A1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129159-B2 | Attachment of molecules to surfaces | SURMODICS, INC. (US) | 2012-03-06 | — | — | US | disclosed |
| US-20110009292-A1 | ATTACHMENT OF MOLECULES TO SURFACES | SURMODICS, INC. (US) | 2011-01-13 | — | — | US | disclosed |
| US-7829317-B2 | Attachment of molecules to surfaces | SURMODICS, INC. (US) | 2010-11-09 | — | — | US | disclosed |
| US-7691787-B2 | Target molecule attachment to surfaces | SURMODICS, INC. (US) | 2010-04-06 | — | — | US | disclosed |
| US-20090042742-A1 | Attachment of molecules to surfaces | SURMODICS, INC. (US) | 2009-02-12 | — | — | US | disclosed |