SCHEMBL9298

SCHEMBL9298

C1=Cc2ccccc2[N]C1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL8322206 0.98 TRPA1 (0.32) TRPA1
SCHEMBL1808702 0.77 TRPA1 (0.31) TRPA1
SCHEMBL9728983 0.77 TRPA1 (0.31) TRPA1
SCHEMBL1162597 0.75
SCHEMBL7354096 0.74 ALDH1A1 (0.31)
SCHEMBL442201 0.71 CHRNB2 (0.31)
SCHEMBL445874 0.71 CHRNB2 (0.31)
SCHEMBL7947507 0.68 TRPA1 (0.35) TRPA1
Bromide SCHEMBL3719760 0.67 TRPA1 (0.34) TRPA1
SCHEMBL443966 0.67 CA12 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2336 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116568677-A piperidin-1-yl-N-pyridin-3-yl-2-oxoacetamide derivatives useful for the treatment of MTAP deficiency and/or MTA accumulating cancers 探戈医药股份有限公司 2023-08-08 CN claimed
EP-3507328-B1 METHOD OF ATTENUATING CONCENTRATION OF ACROLEIN DOW GLOBAL TECHNOLOGIES LLC (US) 2022-07-20 EP claimed
CN-112558409-B Sulfonylimide photoacid generators capable of highly generating acid on line I 常州强力先端电子材料有限公司 2022-05-20 CN claimed
US-11124628-B2 Method of attenuating concerntration of acrolein DOW GLOBAL TECHNOLOGIES LLC (US) 2021-09-21 US claimed
CN-112558409-A Sulfonyl imide photoacid generator capable of generating acid at I line 常州强力先端电子材料有限公司 2021-03-26 CN claimed
US-20190284200-A1 MODULATORS OF THE BETA-3 ADRENERGIC RECEPTOR USEFUL FOR THE TREATMENT OR PREVENTION OF DISORDERS RELATED THERETO ARENA PHARMACEUTICALS, INC. 2019-09-19 US claimed
CN-108101904-B A method of preparing quinoquinazolone derivative 苏州大学张家港工业技术研究院 2019-08-30 CN claimed
US-20190211185-A1 METHOD OF ATTENUATING CONCERNTRATION OF ACROLEIN DOW GLOBAL TECHNOLOGIES LLC 2019-07-11 US claimed
EP-3464292-A1 MODULATORS OF THE BETA-3 ADRENERGIC RECEPTOR USEFUL FOR THE TREATMENT OR PREVENTION OF DISORDERS RELATED THERETO Arena Pharmaceuticals, Inc. (US) 2019-04-10 EP claimed
US-20180258038-A1 N,N-SUBSTITUTED 3-AMINOPYRROLIDINE COMPOUNDS USEFUL AS MONOAMINES REUPTAKE INHIBITORS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2018-09-13 US claimed
EP-0124216-B1 C-20- AND C-23-MODIFIED MACROLIDE DERIVATIVES ELI LILLY AND COMPANY (US) 1988-10-26 EP claimed
CN-87101864-A Pyrazolo [3,4-d] pyrimidine derivatives and production and purposes 1987-11-18 CN claimed
US-4698352-A 4-oxo-1,4-dihydronicotinic acid derivatives, salts thereof, and antibacterial agents containing the same TOYAMA CHEMICAL CO., LTD. (JP) 1987-10-06 US claimed
US-4687853-A COLOR FORMERS BAYER AKTIENGESELLSCHAFT, A CORP OF GERMANY (DE) 1987-08-18 US claimed
EP-0156214-A2 Imidazo [1,5-a] pyridyl methane and imidazo [1,5-b] pyridazinyl methane derivatives, their preparation and recording materials containing them BAYER AG (DE) 1985-10-02 EP claimed
EP-0014402-B1 NOVEL 20-0-ACYLMAYTANSINOIDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Takeda Chemical Industries, Ltd. (JP) 1983-07-20 EP claimed
US-4307016-A FUNGICIDES, PROTOZOACIDES OR ANTITUMOR AGENTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1981-12-22 US claimed
US-4294757-A BLEACHING CELLULOSE FIBERS AND ADDITION OF ALKALI METAL POLYPHOSPHATES AND ALKALI METAL DIETHYLENETRIAMINE PENTA(METHYLENE PHOSPHONAT) TAKEDA CHEMICAL INDUSTRIES, LTD (JP) 1981-10-13 US claimed
US-4256746-A ANTITUMOR AGENTS; MICROBIOCIDES; MITOSIS TAKEDA CHEMICAL INDUSTRIES (JP) 1981-03-17 US claimed
US-4113867-A ANTHELMINTICS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1978-09-12 US claimed