Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.43 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrophosphoric Acid SCHEMBL17311822 | 0.83 | FDPS (0.59) | BLMLMNACYP3A4NFKB1PMP22 | |
| SCHEMBL29008682 | 0.81 | ALDH1A1 (0.48) | BLMLMNACYP3A4NFKB1PMP22 | |
| SCHEMBL5701295 | 0.81 | GABBR2 (0.48) | BLMLMNACYP3A4NFKB1PMP22 | |
| SCHEMBL5701297 | 0.81 | GABBR2 (0.48) | BLMLMNACYP3A4NFKB1PMP22 | |
| Pyrophosphoric Acid SCHEMBL15102978 | 0.80 | BLM (0.56) | BLMLMNACYP3A4NFKB1PMP22 | |
| Pyrophosphoric Acid SCHEMBL15103150 | 0.80 | BLM (0.56) | BLMLMNACYP3A4NFKB1PMP22 | |
| Diaminooctane SCHEMBL15103120 | 0.80 | BLM (0.56) | BLMLMNACYP3A4NFKB1PMP22 | |
| Pyrophosphoric Acid SCHEMBL15102964 | 0.80 | BLM (0.56) | BLMLMNACYP3A4NFKB1PMP22 | |
| Pyrophosphoric Acid SCHEMBL15103002 | 0.80 | BLM (0.56) | BLMLMNACYP3A4NFKB1PMP22 | |
| Pyrophosphoric Acid SCHEMBL15103021 | 0.80 | BLM (0.56) | BLMLMNACYP3A4NFKB1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593437-A1 | GEM-DIPHOSPHONIC ACIDS, A PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. | BOEHRINGER MANNHEIM ITALIA (IT) | 1994-04-27 | — | — | EP | disclosed |