Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.57 |
| ▸ | PPARG | P37231 | 2/20 | 0.57 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.55 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.55 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.48 |
| ▸ | LPL | P06858 | 2/20 | 0.48 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5289171 | 0.83 | HPGD (0.54) | HDAC4MEF2DALDH1A1CA12CA1 | |
| SCHEMBL2958385 | 0.81 | S1PR1 (0.55) | PPARAPPARGS1PR1S1PR4S1PR5 | |
| SCHEMBL10762816 | 0.81 | S1PR1 (0.58) | PPARAPPARGS1PR1S1PR4S1PR5 | |
| SCHEMBL11428645 | 0.80 | ALDH1A1 (0.60) | S1PR1S1PR3ALDH1A1 | |
| SCHEMBL10956825 | 0.80 | ALDH1A1 (0.60) | S1PR1S1PR3ALDH1A1 | |
| SCHEMBL10952015 | 0.80 | ALDH1A1 (0.60) | S1PR1S1PR3ALDH1A1 | |
| SCHEMBL10951825 | 0.80 | ALDH1A1 (0.60) | S1PR1S1PR3ALDH1A1 | |
| SCHEMBL5513033 | 0.80 | ALDH1A1 (0.60) | S1PR1S1PR3ALDH1A1 | |
| SCHEMBL5728257 | 0.80 | FFAR1 (0.56) | PPARAPPARGFFAR1 | |
| SCHEMBL9445945 | 0.80 | S1PR1 (0.53) | S1PR1S1PR4S1PR5S1PR3CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374656-A | Nervous system disorders, gastrointestinal disorders | RHONE-POULENC RORER, S.A. (FR) | 1994-12-20 | — | — | US | disclosed |