Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 6/20 | 0.53 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.53 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.53 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 6/20 | 0.42 |
| ▸ | CA1 | P00915 | 6/20 | 0.42 |
| ▸ | CA2 | P00918 | 6/20 | 0.42 |
| ▸ | CA4 | P22748 | 6/20 | 0.42 |
| ▸ | CA9 | Q16790 | 6/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9445994 | 0.92 | S1PR1 (0.49) | S1PR1S1PR4S1PR5S1PR3FFAR1 | |
| SCHEMBL9181038 | 0.82 | PGK1 (0.46) | CA12CA1CA2CA4CA9 | |
| SCHEMBL9298052 | 0.80 | PPARA (0.57) | S1PR1S1PR4S1PR5S1PR3FFAR1 | |
| SCHEMBL14391952 | 0.77 | S1PR1 (0.55) | S1PR1S1PR4S1PR5S1PR3S1PR2 | |
| SCHEMBL340537 | 0.75 | AKR1C3 (0.55) | CA12CA1CA2CA4CA9 | |
| SCHEMBL5289171 | 0.74 | HPGD (0.54) | CA12CA1CA2CA4CA9 | |
| SCHEMBL6370932 | 0.74 | CFD (0.53) | CA12CA1CA2CA4CA9 | |
| SCHEMBL22338364 | 0.74 | PLAAT3 (0.53) | CA12CA1CA2CA9 | |
| SCHEMBL9112987 | 0.73 | FFAR1 (0.44) | S1PR1S1PR4S1PR5S1PR3S1PR2 | |
| SCHEMBL4406117 | 0.73 | S1PR2 (0.69) | S1PR1S1PR4S1PR3S1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5179085-A | Cerebrovascular disorders | WARNER-LAMBERT COMPANY (US) | 1993-01-12 | — | — | US | disclosed |