Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23929061 | 0.92 | SMN1; SMN2 (0.82) | SMN1; SMN2HSD17B10POLBUSP2HTT | |
| SCHEMBL7131820 | 0.90 | ALDH1A1 (0.55) | SMN1; SMN2HSD17B10TDP1 | |
| SCHEMBL7128542 | 0.81 | ALDH1A1 (0.67) | SMN1; SMN2HSD17B10TSHRKMT2AKDM4E | |
| SCHEMBL24368139 | 0.81 | HSD17B10 (0.91) | SMN1; SMN2HSD17B10USP2HTTTSHR | |
| SCHEMBL936468 | 0.81 | HSD17B10 (0.91) | SMN1; SMN2HSD17B10USP2HTTTSHR | |
| SCHEMBL6999654 | 0.81 | GLA (0.61) | SMN1; SMN2HSD17B10POLBTSHRKMT2A | |
| SCHEMBL26202641 | 0.79 | SMN1; SMN2 (0.57) | SMN1; SMN2HSD17B10USP2HTTTSHR | |
| SCHEMBL10567786 | 0.79 | HSD17B10 (0.87) | SMN1; SMN2HSD17B10USP2HTTTSHR | |
| SCHEMBL9193218 | 0.79 | HSD17B10 (0.95) | SMN1; SMN2HSD17B10USP2HTTTSHR | |
| SCHEMBL20564592 | 0.79 | HSD17B10 (0.95) | SMN1; SMN2HSD17B10USP2HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5376357-A | Magnetic resonance imaging agents | MALLINCKRODT MEDICAL, INC. (US) | 1994-12-27 | — | — | US | disclosed |
| US-5011925-A | Morpholinoamido EDTA derivatives | MALLINCKRODT, INC. (US) | 1991-04-30 | — | — | US | disclosed |