SCHEMBL305771

SCHEMBL305771

O=P(Oc1c[nH]c2cc(Cl)ccc12)(Oc1c[nH]c2cc(Cl)ccc12)Oc1c[nH]c2cc(Cl)ccc12

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 2/20 0.49
NR4A2 P43354 2/20 0.48
ALDH1A1 P00352 1/20 0.46
IDO1 P14902 2/20 0.40
RHEB Q15382 2/20 0.40
DAO P14920 1/20 0.40
SLC6A4 P31645 1/20 0.39
F7 P08709 1/20 0.39
F3 P13726 1/20 0.39
DYRK1A Q13627 2/20 0.38
PYGL P06737 1/20 0.38
HTR2A P28223 1/20 0.38
PARP1 P09874 1/20 0.38
GSK3B P49841 1/20 0.38
TP53 P04637 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL305772 0.87 NR4A2 (0.49) GPR84NR4A2ALDH1A1IDO1RHEB
SCHEMBL3144513 0.87 GPR84 (0.46) GPR84NR4A2ALDH1A1IDO1RHEB
SCHEMBL6409572 0.80 GPR84 (0.49) GPR84IDO1DAOHTR2A
SCHEMBL29051233 0.79 GPR84 (0.55) GPR84NR4A2ALDH1A1IDO1RHEB
SCHEMBL14527902 0.77 NR4A2 (0.55) GPR84NR4A2ALDH1A1IDO1RHEB
SCHEMBL28753980 0.77 GPR84 (0.49) GPR84NR4A2ALDH1A1IDO1RHEB
SCHEMBL9300868 0.77 GPR84 (0.49) GPR84NR4A2ALDH1A1IDO1RHEB
SCHEMBL9299192 0.76 NR4A2 (0.42) GPR84NR4A2ALDH1A1IDO1DYRK1A
SCHEMBL1853697 0.75 SLC22A6 (0.54) GPR84NR4A2ALDH1A1
SCHEMBL9300871 0.74 SLC22A6 (0.62) GPR84NR4A2ALDH1A1IDO1RHEB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 324 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4733317-A2 NEUTRALIZING ANTI-INFLUENZA B ANTIBODIES AND USES THEREOF MedImmune, LLC (US) 2026-04-29 EP disclosed
EP-3169407-B1 NEUTRALIZING ANTI-INFLUENZA B ANTIBODIES AND USES THEREOF MEDIMMUNE LLC (US) 2026-02-11 EP disclosed
US-12492240-B2 Neutralizing anti-influenza A antibodies and uses thereof MEDIMMUNE, LLC (US) 2025-12-09 US disclosed
US-12487180-B2 Device and methods for quantifying analytes introduction Life Technologies Corporation (US) 2025-12-02 US disclosed
US-20250302952-A1 METHOD OF TREATING INFLUENZA A MEDIMMUNE, LLC 2025-10-02 US disclosed
US-20250263470-A1 NEUTRALIZING ANTI-INFLUENZA B ANTIBODIES AND USES THEREOF MEDIMMUNE LLC (US) 2025-08-21 US disclosed
US-12357692-B2 Method of treating influenza A MEDIMMUNE, LLC (US) 2025-07-15 US disclosed
EP-4565237-A1 PHARMACEUTICAL COMPOSITIONS AND USES THEREOF FOR THE TREATMENT OF GLIOMA Chimerix, Inc. (US) 2025-06-11 EP disclosed
US-12325740-B2 Neutralizing anti-influenza B antibodies and uses thereof MEDIMMUNE, LLC (US) 2025-06-10 US disclosed
US-20250152728-A1 Method And Molecules THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2025-05-15 US disclosed
WO-2004042347-A2 COMPOSITIONS AND METHODS FOR DETECTION AND ISOLATION OF PHOSPHORYLATED MOLECULES MOLECULAR PROBES, INC. (US) 2004-05-21 WO disclosed
US-20040038306-A1 Compositions and methods for detection and isolation of phosphorylated molecules MOLECULAR PROBES, INC. 2004-02-26 US disclosed
EP-1334205-A1 METHOD FOR IDENTIFYING LISTERIA MONOCYTOGENES AND CULTURE MEDIUM Biomerieux S.A. (FR) 2003-08-13 EP disclosed
US-20030073149-A1 Antibody complexes and methods for immunolabeling Life Technologies Corporation 2003-04-17 US disclosed
WO-2003030817-A2 ANTIBODY COMPLEXES AND METHODS FOR IMMUNOLABELING MOLECULAR PROBES, INC. (US) 2003-04-17 WO disclosed
WO-2002040705-A1 METHOD FOR IDENTIFYING LISTERIA MONOCYTOGENES AND CULTURE MEDIUM BIOMERIEUX S.A. (FR) 2002-05-23 WO disclosed
EP-0775215-B1 CHEMILUMINESCENCE ASSAYS BASED ON INDOXYL SUBSTRATES OR THIOINDOXYL SUBSTRATES MEDILITE DIAGNOSTIKA (US) 2001-12-19 EP disclosed
EP-0775215-A1 CHEMILUMINESCENCE ASSAYS BASED ON INDOXYL SUBSTRATES, THIOINDOXYL SUBSTRATES AND OTHER SUBSTRATES MEDILITE DIAGNOSTIKA (US) 1997-05-28 EP disclosed
US-5589328-A CHEMICAL INTERMEDIATES OR METABOLITES FOR IMMUNOASSAY MEDILITE DIAGNOSTIKA 1996-12-31 US disclosed
WO-1996004400-A1 CHEMILUMINESCENCE ASSAYS BASED ON INDOXYL SUBSTRATES, THIOINDOXYL SUBSTRATES AND OTHER SUBSTRATES MEDILITE DIAGNOSTIKA (US) 1996-02-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250152728-A1 Method And Molecules PAICS, EPCAM, SQLE GPR84 1022/4885NR4A2 2643/4885ALDH1A1 27/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.