Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | GSK3A | P49840 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MPI | P34949 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6777058 | 0.80 | POLB (0.47) | SMN1; SMN2LMNAHCAR1MEN1KMT2A | |
| SCHEMBL10689024 | 0.73 | SMN1; SMN2 (0.40) | SMN1; SMN2LMNAKDM4EHCAR1MEN1 | |
| SCHEMBL482140 | 0.70 | SMN1; SMN2 (1.00) | SMN1; SMN2LMNAKDM4EMEN1KMT2A | |
| SCHEMBL4544224 | 0.67 | SMN1; SMN2 (0.64) | SMN1; SMN2LMNAKDM4EMEN1KMT2A | |
| SCHEMBL10689850 | 0.64 | SMN1; SMN2 (0.55) | SMN1; SMN2LMNAKDM4EHCAR1MEN1 | |
| SCHEMBL6081429 | 0.62 | KDM4E (0.42) | SMN1; SMN2LMNAKDM4EMEN1KMT2A | |
| SCHEMBL6412476 | 0.62 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAKDM4EMEN1KMT2A | |
| SCHEMBL11775647 | 0.61 | SMN1; SMN2 (0.47) | SMN1; SMN2KDM4EMEN1KMT2AGAA | |
| SCHEMBL5963314 | 0.61 | HPGD (0.68) | SMN1; SMN2LMNAKDM4EMEN1KMT2A | |
| SCHEMBL3655311 | 0.61 | TSHR (0.48) | SMN1; SMN2LMNAKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328803-A | Alkali developable solutions with carboxy group binders and monomer with initiators | FUJI PHOTO FILM CO., LTD. (JP) | 1994-07-12 | — | — | US | disclosed |
| EP-0062853-B1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED 3-HYDROXY-1,2,4-TRIAZOLES | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-11-06 | — | — | EP | disclosed |
| US-4467098-A | BY CYCLIZATION OF SEMICARBAZIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-08-21 | — | — | US | disclosed |
| EP-0062853-A2 | Process for the preparation of substituted 3-hydroxy-1,2,4-triazoles | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-10-20 | — | — | EP | disclosed |