Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | GSK3A | P49840 | 3/20 | 0.39 |
| ▸ | GSK3B | P49841 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MPI | P34949 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL482140 | 0.65 | SMN1; SMN2 (1.00) | SMN1; SMN2GAAGSK3AGSK3BTSHR | |
| SCHEMBL9299526 | 0.62 | SMN1; SMN2 (0.53) | SMN1; SMN2GAAGSK3AGSK3BTSHR | |
| SCHEMBL4544224 | 0.62 | SMN1; SMN2 (0.64) | SMN1; SMN2GAAGSK3AGSK3BTSHR | |
| SCHEMBL11775647 | 0.61 | SMN1; SMN2 (0.47) | SMN1; SMN2GAAGSK3AGSK3BTSHR | |
| SCHEMBL5963314 | 0.61 | HPGD (0.68) | SMN1; SMN2GAAGSK3AGSK3BTSHR | |
| SCHEMBL3655311 | 0.61 | TSHR (0.48) | SMN1; SMN2GAAGSK3AGSK3BTSHR | |
| SCHEMBL7772227 | 0.60 | TSHR (0.42) | SMN1; SMN2GAAGSK3AGSK3BTSHR | |
| SCHEMBL8128786 | 0.58 | GSK3A (0.54) | SMN1; SMN2GAAGSK3AGSK3BTSHR | |
| SCHEMBL1232067 | 0.57 | TSHR (0.48) | SMN1; SMN2GAAGSK3AGSK3BTSHR | |
| SCHEMBL265945 | 0.57 | SMN1; SMN2 (0.52) | SMN1; SMN2GAAGSK3AGSK3BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050215487-A1 | Conjugates comprising an nsaid and a sugar and uses thereof | HOLICK MICHAEL F | 2005-09-29 | — | — | US | disclosed |
| US-4997919-A | Azo direct dyes containing a non-reactive triazinyl moiety | CIBA-GEIGY CORPORATION (US) | 1991-03-05 | — | — | US | disclosed |
| EP-0348344-A1 | Azo dyes | CIBA-GEIGY AG (CH) | 1989-12-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050215487-A1 | Conjugates comprising an nsaid and a sugar and uses thereof | FUT6, FUT5, CD44 | SMN1; SMN2 2487/4885GAA 383/4885GSK3A 3372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.