Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9131146 | 0.78 | MAPT (0.36) | KMT2AHTTMEN1MAPTALDH1A1 | |
| SCHEMBL28274064 | 0.75 | TGM2 (0.57) | KMT2AHTTMEN1MAPTALDH1A1 | |
| SCHEMBL13921951 | 0.75 | SMN1; SMN2 (0.44) | KMT2AHTTMEN1MAPTALDH1A1 | |
| SCHEMBL1285514 | 0.74 | MAPT (0.56) | KMT2AHTTMEN1MAPTALDH1A1 | |
| SCHEMBL5005472 | 0.73 | KMT2A (0.62) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL30856804 | 0.72 | SMN1; SMN2 (0.72) | KMT2AHTTMEN1MAPTALDH1A1 | |
| SCHEMBL2144155 | 0.72 | ALDH1A1 (0.43) | KMT2AHTTMEN1MAPTALDH1A1 | |
| SCHEMBL3305172 | 0.71 | MAPT (0.51) | KMT2AHTTMEN1MAPTALDH1A1 | |
| SCHEMBL28688793 | 0.71 | GPR35 (0.53) | KMT2AHTTMEN1MAPTALDH1A1 | |
| SCHEMBL30613334 | 0.71 | MAPT (0.51) | KMT2AHTTMEN1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5316704-A | Deformed into elongation configuration; surgery insertion | KABI PHARMACIA OPHTHALMICS INC. (US) | 1994-05-31 | — | — | US | claimed |