Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 15/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9299345 | 0.79 | ALDH1A1 (0.43) | — | |
| SCHEMBL9298462 | 0.79 | SCN9A (0.35) | — | |
| SCHEMBL9299611 | 0.72 | KMT2A (0.37) | — | |
| SCHEMBL9298666 | 0.69 | CA1 (0.31) | — | |
| SCHEMBL5494097 | 0.69 | — | — | |
| SCHEMBL17369088 | 0.67 | ALPL (0.50) | GRIN2BGRIN1 | |
| SCHEMBL9300341 | 0.66 | HTR6 (0.30) | — | |
| SCHEMBL17399639 | 0.66 | CCNC (0.41) | NPSR1JAK2JAK1TYK2JAK3 | |
| SCHEMBL9299474 | 0.66 | NOTUM (0.39) | — | |
| SCHEMBL32889379 | 0.66 | NPSR1 (0.43) | GRIN2BNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5302712-A | Intermediates for cephem compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-12 | — | — | US | disclosed |
| US-5215982-A | Antibiotics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-06-01 | — | — | US | disclosed |
| EP-0427248-A2 | New cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-15 | — | — | EP | disclosed |