Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 3/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9299143 | 0.92 | GPR84 (0.43) | DUTGPR84NSD2ABL1PPARG | |
| SCHEMBL1781944 | 0.82 | DUT (0.39) | DUTGPR84NSD2ABL1PPARG | |
| SCHEMBL15901906 | 0.78 | HDAC1 (0.44) | DUTABL1 | |
| SCHEMBL8721414 | 0.73 | GPR84 (0.38) | GPR84PLA2G7NSD2ABL1PPARG | |
| SCHEMBL2252126 | 0.72 | IDO1 (0.53) | DUTL3MBTL1 | |
| SCHEMBL13677532 | 0.72 | GPR84 (0.47) | GPR84NSD2ABL1PPARGRIN1 | |
| SCHEMBL11482682 | 0.71 | DUT (0.37) | DUTPPARG | |
| SCHEMBL21068770 | 0.71 | DUT (0.37) | DUTPPARG | |
| SCHEMBL21268599 | 0.71 | IDO1 (0.42) | DUT | |
| SCHEMBL3168839 | 0.71 | GABRA1 (0.47) | HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296492-A | Certain chroman derivatives useful for treating symptoms caused by contraction of smooth muscles, circulatory diseases or epilepsy | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0518342-A1 | Chroman derivatives | Nippon Kayaku Kabushiki Kaisha (JP) | 1992-12-16 | — | — | EP | disclosed |