SCHEMBL9300546

SCHEMBL9300546

Clc1ncn(-c2ccccc2)n1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.49
SMN1; SMN2 Q16637 7/20 0.49
HPGD P15428 4/20 0.49
NPC1 O15118 3/20 0.49
RAB9A P51151 3/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
TDP1 Q9NUW8 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
TSHR P16473 2/20 0.47
ALOX15 P16050 1/20 0.47
ALDH1A1 P00352 3/20 0.45
NOTUM Q6P988 1/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
ALOX15B O15296 1/20 0.41
FGFR1 P11362 1/20 0.41
KDM4E B2RXH2 1/20 0.41
TP53 P04637 3/20 0.40
POLB P06746 2/20 0.40
PKM P14618 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3748429 0.79 MKNK1 (0.47) MAPTSMN1; SMN2HPGDNPC1RAB9A
SCHEMBL8109901 0.74 SMN1; SMN2 (0.47) MAPTSMN1; SMN2HPGDNPC1RAB9A
SCHEMBL7044640 0.74 HPGD (0.49) MAPTSMN1; SMN2HPGDNPC1RAB9A
SCHEMBL7044636 0.74 SMN1; SMN2 (0.51) MAPTSMN1; SMN2HPGDNPC1RAB9A
SCHEMBL2360711 0.74 MAPT (0.47) MAPTSMN1; SMN2HPGDNPC1RAB9A
SCHEMBL4857635 0.74 MAPT (0.47) MAPTSMN1; SMN2HPGDNPC1RAB9A
SCHEMBL2210435 0.74 SMN1; SMN2 (0.47) MAPTSMN1; SMN2HPGDNPC1RAB9A
SCHEMBL1788009 0.74 SMN1; SMN2 (0.47) MAPTSMN1; SMN2HPGDNPC1RAB9A
SCHEMBL4886785 0.74 HPGD (0.47) MAPTSMN1; SMN2HPGDNPC1RAB9A
SCHEMBL458419 0.72 NPC1 (0.46) MAPTSMN1; SMN2HPGDNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5328803-A Alkali developable solutions with carboxy group binders and monomer with initiators FUJI PHOTO FILM CO., LTD. (JP) 1994-07-12 US disclosed