SCHEMBL9300608

SCHEMBL9300608

O=C(O)/C=C\C(=O)OC(=O)c1ccc(C(=O)OC(=O)/C=C\C(=O)O)cc1

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.45
MAPT P10636 4/20 0.45
KMT2A Q03164 2/20 0.45
HCAR2 Q8TDS4 8/20 0.44
LMNA P02545 2/20 0.44
HTT P42858 2/20 0.44
THRB P10828 1/20 0.44
HPGD P15428 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
TSHR P16473 2/20 0.39
TP53 P04637 1/20 0.39
EGLN1 Q9GZT9 1/20 0.39
EGLN3 Q9H6Z9 1/20 0.39
KDM4E B2RXH2 1/20 0.38
ATM Q13315 1/20 0.38
F2 P00734 1/20 0.38
MEN1 O00255 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27590291 0.92 MAPT (0.58) ALDH1A1MAPTKMT2AHCAR2LMNA
SCHEMBL15563736 0.92 HCAR2 (0.50) ALDH1A1MAPTKMT2AHCAR2LMNA
SCHEMBL3235668 0.92 HCAR2 (0.50) ALDH1A1MAPTKMT2AHCAR2LMNA
Hydrochloric Acid SCHEMBL9497409 0.90 HCAR2 (0.49) ALDH1A1MAPTKMT2AHCAR2LMNA
Hydrochloric Acid SCHEMBL9497418 0.90 HCAR2 (0.49) ALDH1A1MAPTKMT2AHCAR2LMNA
SCHEMBL33341 0.88 ALDH1A1 (0.37) ALDH1A1MAPTKMT2AHCAR2LMNA
SCHEMBL11236588 0.87 TSHR (0.52) ALDH1A1MAPTKMT2ATSHRTP53
SCHEMBL18838919 0.84 LMNA (0.56) ALDH1A1MAPTKMT2ALMNAHPGD
SCHEMBL27581022 0.84 LMNA (0.56) ALDH1A1MAPTKMT2ALMNAHPGD
SCHEMBL9138895 0.84 HCAR2 (0.43) ALDH1A1MAPTKMT2AHCAR2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113881031-B Polyether polyol and preparation method and application thereof 中国石油化工股份有限公司 2024-06-28 CN claimed
CN-111087597-B Preparation method of high-activity polyether polyol 中国石油化工股份有限公司 2023-01-24 CN claimed
CN-113881031-B Polyether polyol and preparation method and application thereof 中国石油化工股份有限公司 2024-06-28 CN disclosed
CN-112694620-B Preparation method of hyperbranched polymer 中国石油化工股份有限公司 2023-11-28 CN disclosed
CN-113801315-B End-capped polyether containing phenylethane oxide and preparation method and application thereof 中国石油化工股份有限公司 2023-08-29 CN disclosed
CN-111087599-B Process for preparing high molecular weight polyethylene oxides 中国石油化工股份有限公司 2023-04-07 CN disclosed
CN-111087600-B Polyurethane elastomer resin and preparation method thereof 中国石油化工股份有限公司 2023-03-03 CN disclosed
CN-111087597-B Preparation method of high-activity polyether polyol 中国石油化工股份有限公司 2023-01-24 CN disclosed
CN-112694607-B Polyether polyol and preparation method and application thereof 中国石油化工股份有限公司 2022-12-09 CN disclosed
CN-113881031-A Polyether polyol and preparation method and application thereof 中国石油化工股份有限公司 2022-01-04 CN disclosed
CN-113801315-A End-capped polyether containing phenylethane oxide, preparation method and application thereof 中国石油化工股份有限公司 2021-12-17 CN disclosed
CN-113801333-A Preparation method of amphiphilic hyperbranched polymer 中国石油化工股份有限公司 2021-12-17 CN disclosed
CN-112694607-A Polyether polyol and preparation method and application thereof 中国石油化工股份有限公司 2021-04-23 CN disclosed
CN-112694620-A Method for producing hyperbranched polymers 中国石油化工股份有限公司 2021-04-23 CN disclosed
CN-111087599-A Process for preparing high molecular weight polyethylene oxides 中国石油化工股份有限公司 2020-05-01 CN disclosed
CN-111087597-A Preparation method of high-activity polyether polyol 中国石油化工股份有限公司 2020-05-01 CN disclosed
CN-111087598-A Preparation and use method of inorganic supported phosphazene catalyst 中国石油化工股份有限公司 2020-05-01 CN disclosed
CN-111087600-A Polyurethane elastomer resin and preparation method thereof 中国石油化工股份有限公司 2020-05-01 CN disclosed
US-5344674-A Protective coatings for metal surfaces PHILLIPS PETROLEUM COMPANY (US) 1994-09-06 US disclosed