SCHEMBL11236588

SCHEMBL11236588

O=C(/C=C/C(=O)OC(=O)c1ccc(C(=O)O)cc1)OC(=O)c1ccc(C(=O)O)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.52
TP53 P04637 1/20 0.52
SRD5A2 P31213 3/20 0.46
ALDH1A1 P00352 4/20 0.45
CA1 P00915 3/20 0.44
CA2 P00918 3/20 0.44
CA12 O43570 1/20 0.44
CA3 P07451 1/20 0.44
TYR P14679 1/20 0.44
DRD1 P21728 1/20 0.44
CA4 P22748 1/20 0.44
CA6 P23280 1/20 0.44
CA5A P35218 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
CA14 Q9ULX7 1/20 0.44
CA5B Q9Y2D0 1/20 0.44
ALOX15 P16050 1/20 0.43
TPMT P51580 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adipic Acid SCHEMBL4757335 0.88 ALDH1A1 (0.41) TSHRTP53SRD5A2ALDH1A1CA1
SCHEMBL9300608 0.87 ALDH1A1 (0.45) TSHRTP53ALDH1A1KMT2AMAPT
SCHEMBL18838919 0.84 LMNA (0.56) TSHRTP53ALDH1A1SMN1; SMN2DAO
SCHEMBL27581022 0.84 LMNA (0.56) TSHRTP53ALDH1A1SMN1; SMN2DAO
SCHEMBL1269049 0.84 TSHR (0.67) TSHRTP53SRD5A2ALDH1A1CA1
SCHEMBL110030 0.84 TSHR (0.67) TSHRTP53SRD5A2ALDH1A1CA1
SCHEMBL15129970 0.84 TSHR (0.67) TSHRTP53SRD5A2ALDH1A1CA1
SCHEMBL15798253 0.83 TSHR (0.48) TSHRTP53SRD5A2ALDH1A1CA1
SCHEMBL28164884 0.81 TSHR (0.63) TSHRTP53SRD5A2ALDH1A1CA1
SCHEMBL28020626 0.81 CES2 (0.48) CA1CA2SMN1; SMN2CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113825738-A Method for producing metal organic frameworks 阿特密斯株式会社 2021-12-21 CN disclosed
US-4309297-A Heat storage material NIPPON PETROCHEMICALS COMPANY, LTD. (JP) 1982-01-05 US disclosed