Sulfuric Acid

Sulfuric Acid

SCHEMBL9300936

CCNc1ccc(NCC)c(C)c1.O=S(=O)(O)O

nearest known ligand 0.43

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2A known ✓ P08913 1/20 0.35
ADRA2B known ✓ P18089 1/20 0.35
ADRA2C known ✓ P18825 1/20 0.35
RECQL P46063 3/20 0.43
CYP3A4 P08684 2/20 0.43
TSHR P16473 1/20 0.43
ALDH1A1 P00352 6/20 0.40
IDO1 P14902 1/20 0.39
MAPT P10636 3/20 0.38
HPGD P15428 3/20 0.38
GAA P10253 2/20 0.38
THRB P10828 2/20 0.38
KDM4E B2RXH2 2/20 0.38
HTT P42858 1/20 0.38
GFER P55789 1/20 0.38
PLEC Q15149 1/20 0.38
VDR P11473 3/20 0.38
LMNA P02545 3/20 0.36
POLB P06746 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL28617571 0.89 ALDH1A1 (0.49) RECQLCYP3A4TSHRALDH1A1IDO1
SCHEMBL9172326 0.89 RECQL (0.47) RECQLCYP3A4TSHRALDH1A1IDO1
Sulfuric Acid SCHEMBL8662740 0.89 ALDH1A1 (0.37) RECQLCYP3A4TSHRALDH1A1IDO1
Hydrochloric Acid SCHEMBL6357371 0.87 RECQL (0.46) RECQLCYP3A4TSHRALDH1A1IDO1
Sulfuric Acid SCHEMBL9564309 0.85 GAA (0.40) RECQLCYP3A4TSHRALDH1A1MAPT
Sulfuric Acid SCHEMBL11565419 0.85 CYP3A4 (0.37) RECQLCYP3A4TSHRALDH1A1IDO1
SCHEMBL11332762 0.82 MAPT (0.47) RECQLCYP3A4TSHRALDH1A1IDO1
Sulfuric Acid SCHEMBL7749074 0.81 ALDH1A1 (0.47) RECQLCYP3A4TSHRALDH1A1MAPT
SCHEMBL7774943 0.80 RECQL (0.43) RECQLCYP3A4TSHRALDH1A1IDO1
Sulfuric Acid SCHEMBL11044859 0.80 ALDH1A1 (0.46) RECQLCYP3A4TSHRALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5360700-A Single stabilizing step, magenta and cyan couplers, ferric salt of organic acid KONICA CORPORATION (JP) 1994-11-01 US disclosed
EP-0250219-B1 Method of storing photographic processing solution KONISHIROKU PHOTO IND (JP) 1994-03-30 EP disclosed
US-5180656-A Dye developer, a chloride bleach-fixer and silver halide emulsions KONICA CORPORATION (JP) 1993-01-19 US disclosed
US-4814260-A USING DEVELOPER WITH SUBSTITUTED HYDROXYLAMINE PRESERVATIVE; BLEACH-FIXER WITH REDUCED AMOUNTS OF AMINOPOLYCARBOXYLIC ACID AND SULFITE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1989-03-21 US disclosed