Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4824966 | 0.92 | THRB (0.39) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL15475367 | 0.82 | THRB (0.44) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL9300390 | 0.80 | TSHR (0.51) | THRBTSHRALDH1A1 | |
| SCHEMBL11573487 | 0.80 | THRB (0.43) | THRBTSHRPOLBAPEX1HTT | |
| Di(Hydroxyethyl)Ether SCHEMBL491939 | 0.80 | TSHR (0.42) | TSHRALDH1A1 | |
| SCHEMBL629901 | 0.80 | THRB (0.68) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL2367411 | 0.80 | THRB (0.68) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL2804854 | 0.80 | THRB (0.68) | THRBTSHRPOLBAPEX1HTT | |
| Di(Hydroxyethyl)Ether SCHEMBL18317889 | 0.80 | THRB (0.68) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL33376 | 0.80 | THRB (0.68) | THRBTSHRPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5326840-A | Radiation-sensitive mixture containing novel polymers embodying units composed of amides of α, β-unsaturated carboxylic acids as binders | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-07-05 | — | — | US | disclosed |