Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 9/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2804854 | 1.00 | THRB (0.68) | THRBTSHRMEN1KMT2AMAPK1 | |
| SCHEMBL863839 | 1.00 | THRB (0.68) | THRBTSHRMEN1KMT2AMAPK1 | |
| SCHEMBL9860990 | 1.00 | THRB (0.68) | THRBTSHRMEN1KMT2AMAPK1 | |
| Di(Hydroxyethyl)Ether SCHEMBL18317889 | 1.00 | THRB (0.68) | THRBTSHRMEN1KMT2AMAPK1 | |
| SCHEMBL2809295 | 1.00 | THRB (0.68) | THRBTSHRMEN1KMT2AMAPK1 | |
| Tetraethylene Glycol SCHEMBL8659912 | 1.00 | THRB (0.68) | THRBTSHRMEN1KMT2AMAPK1 | |
| SCHEMBL33376 | 1.00 | THRB (0.68) | THRBTSHRMEN1KMT2AMAPK1 | |
| SCHEMBL2367411 | 1.00 | THRB (0.68) | THRBTSHRMEN1KMT2AMAPK1 | |
| SCHEMBL864145 | 1.00 | THRB (0.68) | THRBTSHRMEN1KMT2AMAPK1 | |
| SCHEMBL61385 | 1.00 | THRB (0.68) | THRBTSHRMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 218 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150335568-A1 | RADIATION-CURABLE, STABLE NAIL GEL COMPOSITIONS AND METHODS OF PREPARATION AND USE | MYCONE DENTAL CORPORATION (US) | 2015-11-26 | — | — | US | claimed |
| EP-2863883-A1 | RADIATION-CURABLE, STABLE NAIL GEL COMPOSITIONS AND METHODS OF PREPARATION AND USE | Mycone Dental Supply Company Inc. (US) | 2015-04-29 | — | — | EP | claimed |
| WO-2013192515-A1 | RADIATION-CURABLE, STABLE NAIL GEL COMPOSITIONS AND METHODS OF PREPARATION AND USE | MYCONE DENTAL SUPPLY COMPANY, INC. (US) | 2013-12-27 | — | — | WO | claimed |
| US-8329845-B2 | Divided redox-curing type composition | KURARAY NORITAKE DENTAL INC. (JP) | 2012-12-11 | — | — | US | claimed |
| US-7855242-B2 | Dental resin composition, method of manufacture, and method of use thereof | PENTRON CLINICAL TECHNOLOGIES LLC (US) | 2010-12-21 | — | — | US | claimed |
| US-7275933-B2 | Method of manufacturing dental restorations | PENTRON CLINICAL TECHNOLOGIES, LLC (US) | 2007-10-02 | — | — | US | claimed |
| US-20070049656-A1 | DENTAL RESIN COMPOSITION, METHOD OF MANUFACTURE, AND METHOD OF USE THEREOF | PENTRON CLINICAL TECHNOLOGIES, INC (US) | 2007-03-01 | — | — | US | claimed |
| US-20040249015-A1 | Method of manufacturing dental restorations | KERR CORPORATION | 2004-12-09 | — | — | US | claimed |
| US-6787584-B2 | BIODEGRADABLE MACROMONOMER HAVING TERMINAL ACRYLATE OR METHACRYLATE GROUP(S) (ACRYLATED POLYLACTONE); A CURING COMPOSITION; A FILLER OF BIOACTIVE GLASS, APATITES, AND OTHER (METH)ACRYLATES | PENTRON CORPORATION | 2004-09-07 | — | — | US | claimed |
| WO-2002078646-A1 | DENTAL COMPOSITIONS | PENTRON CORPORATION (US) | 2002-10-10 | — | — | WO | claimed |
| US-6455608-B1 | CURABLE DENTAL FORMULATION COMPRISING DEGRADABLE MACROMONOMERS HAVING ONE OR MORE TERMINAL ACRYLATE OR METHACRYLATE FUNCTIONALITY, A CURING AGENT; PREPARING A SITE TO BE RESTORED IN A TOOTH AND APPLYING ABOVE FORMULATION | JENERIC/PENTRON INCORPORATED | 2002-09-24 | — | — | US | claimed |
| US-20020120033-A1 | Biodegradable macromonomer having terminal acrylate or methacrylate group(s) (acrylated polylactone); a curing composition; a filler of bioactive glass, apatites, and other (meth)acrylates | KERR CORPORATION | 2002-08-29 | — | — | US | claimed |
| EP-1202701-A1 | DENTAL COMPOSITIONS COMPRISING DEGRADABLE POLYMERS | JENERIC/PENTRON Incorporated (US) | 2002-05-08 | — | — | EP | claimed |
| WO-2001012129-A1 | DENTAL COMPOSITIONS COMPRISING DEGRADABLE POLYMERS | JENERIC/PENTRON INCORPORATED (US) | 2001-02-22 | — | — | WO | claimed |
| EP-0313665-B1 | ACTINIC RADIATION-CURABLE COMPOSITION FOR CAST POLYMERIZATION AND PRODUCT OF CAST POLYMERIZATION | MITSUBISHI RAYON CO., LTD. (JP) | 1993-02-03 | — | — | EP | claimed |
| US-4985472-A | ACRYLATED POLYISOCYANATE | MITSUBISHI RAYON COMPANY, LTD. (JP) | 1991-01-15 | — | — | US | claimed |
| EP-0313665-A1 | ACTINIC RADIATION-CURABLE COMPOSITION FOR CAST POLYMERIZATION AND PRODUCT OF CAST POLYMERIZATION | MITSUBISHI RAYON CO., LTD. (JP) | 1989-05-03 | — | — | EP | claimed |
| CN-122094989-A | Polymer, water repellent, fiber product and method for producing fiber product | — | 2026-05-26 | — | — | CN | disclosed |
| EP-0218229-A2 | Thermoplastic resin composition and process for its preparation | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1987-04-15 | — | — | EP | disclosed |
| US-4170582-A | Process for preparing a polymer resin aqueous dispersion | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1979-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070049656-A1 | DENTAL RESIN COMPOSITION, METHOD OF MANUFACTURE, AND METHOD OF USE THEREOF | CAD, MMAB, DNMT3A | THRB 1953/4885TSHR 4073/4885MEN1 2776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.