Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 4/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SGMS1 | Q86VZ5 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301802 | 0.87 | TBXA2R (0.48) | TBXA2RTBXAS1TP53SGMS1ALDH1A1 | |
| SCHEMBL9301142 | 0.81 | SGMS1 (0.62) | TBXA2RTBXAS1TP53SGMS1ALDH1A1 | |
| SCHEMBL5008126 | 0.80 | KDM4E (0.57) | TP53ALDH1A1HTTSMN1; SMN2MEN1 | |
| SCHEMBL9514120 | 0.79 | TBXA2R (0.61) | TBXA2RTBXAS1SGMS1POLBALDH1A1 | |
| SCHEMBL9301427 | 0.78 | LMNA (0.45) | POLBALDH1A1GAAHTTSMN1; SMN2 | |
| SCHEMBL9512078 | 0.78 | HTT (0.53) | TBXA2RTBXAS1SGMS1POLBALDH1A1 | |
| SCHEMBL9514132 | 0.76 | TP53 (0.57) | TBXA2RTBXAS1TP53ALDH1A1GAA | |
| SCHEMBL9510541 | 0.72 | TBXA2R (0.59) | TBXA2RTBXAS1TP53SGMS1ALDH1A1 | |
| SCHEMBL9303178 | 0.71 | ALDH1A1 (0.53) | ALDH1A1GAAHTTMEN1KMT2A | |
| SCHEMBL13125981 | 0.70 | S1PR4 (0.52) | TP53ALDH1A1HTTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5360909-A | THROMBOXANE A2 ANTAGONIST | TERUMO KABUSHIKI KAISHA (JP) | 1994-11-01 | — | — | US | disclosed |
| EP-0562796-A1 | Phenoxyacetic acid compounds and medical preparations containing them | TERUMO KABUSHIKI KAISHA (JP) | 1993-09-29 | — | — | EP | disclosed |