Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8850951 | 0.77 | HTT (0.32) | — | |
| SCHEMBL19924985 | 0.73 | LMNA (0.41) | LMNAHSD17B10FDPSTSHRHPGD | |
| SCHEMBL16244342 | 0.72 | LMNA (0.44) | LMNAHSD17B10FDPSTSHRCYP3A4 | |
| SCHEMBL4346472 | 0.72 | LMNA (0.44) | LMNAHSD17B10FDPSTSHRCYP3A4 | |
| SCHEMBL29372293 | 0.72 | TSHR (0.50) | HSD17B10TSHRHPGDTP53CYP1A2 | |
| SCHEMBL9446509 | 0.71 | ALOX15 (0.42) | LMNAHSD17B10TSHRCYP3A4CYP2C19 | |
| SCHEMBL28492541 | 0.70 | LMNA (0.39) | LMNAHSD17B10FDPSTSHRSOAT1 | |
| SCHEMBL28492539 | 0.70 | LMNA (0.39) | LMNAHSD17B10FDPSTSHRSOAT1 | |
| SCHEMBL28419918 | 0.70 | SMPD1 (0.37) | LMNAHSD17B10FDPSTSHRSOAT1 | |
| SCHEMBL29063417 | 0.69 | LMNA (0.41) | LMNAHSD17B10FDPSTSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5364691-A | Alk-1-enyloxy carbonates | ISP INVESTMENTS INC. (US) | 1994-11-15 | — | — | US | disclosed |
| US-5358978-A | Protective coatings and reactant diluents; wear resistance; solvent, acid and alkali resistance; photoresists | ISP INVESTMENTS INC. (US) | 1994-10-25 | — | — | US | disclosed |
| US-5276174-A | Alk-1-enyloxy carbonates | ISP INVESTMENTS INC. (US) | 1994-01-04 | — | — | US | disclosed |
| US-5254710-A | Radiation curable | ISP INVESTMENTS INC. (US) | 1993-10-19 | — | — | US | disclosed |