Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.56 |
| ▸ | MMP1 | P03956 | 4/20 | 0.51 |
| ▸ | MMP2 | P08253 | 4/20 | 0.51 |
| ▸ | MMP9 | P14780 | 4/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | NMT1 | P30419 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13113092 | 0.78 | TGM2 (0.59) | TGM2MMP1MMP2MMP9EGFR | |
| SCHEMBL29246294 | 0.76 | TGM2 (0.61) | TGM2MMP1MMP2MMP9EGFR | |
| SCHEMBL3224667 | 0.76 | ALDH1A1 (0.74) | TGM2MMP1MMP2MMP9EGFR | |
| SCHEMBL10339281 | 0.76 | ALDH1A1 (0.74) | TGM2MMP1MMP2MMP9EGFR | |
| SCHEMBL30764065 | 0.76 | ALDH1A1 (0.74) | TGM2MMP1MMP2MMP9EGFR | |
| SCHEMBL13039692 | 0.76 | ALDH1A1 (0.57) | TGM2MMP1MMP2MMP9EGFR | |
| SCHEMBL28108366 | 0.75 | TGM2 (0.59) | TGM2MMP1MMP2MMP9EGFR | |
| SCHEMBL15708801 | 0.75 | ALDH1A1 (0.69) | TGM2MMP1MMP2MMP9EGFR | |
| SCHEMBL15709144 | 0.74 | TGM2 (0.63) | TGM2MMP1MMP2MMP9EGFR | |
| SCHEMBL13100949 | 0.74 | ALDH1A1 (0.55) | TGM2MMP1MMP2MMP9EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5369109-A | Optically active esters of 7-substituted 3,5-difunctionalized 6-heptenoic acids | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1994-11-29 | — | — | US | disclosed |