Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.49 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.49 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CFTR | P13569 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25143785 | 0.88 | SLC6A3 (0.54) | SLC6A3SLC6A4ALDH1A1LMNATSHR | |
| SCHEMBL2093835 | 0.85 | ALDH1A1 (0.64) | SLC6A3SLC6A4ALDH1A1LMNATSHR | |
| SCHEMBL69464 | 0.85 | SLC6A3 (0.67) | SLC6A3SLC6A4ALDH1A1LMNATSHR | |
| SCHEMBL7168951 | 0.85 | SLC6A3 (0.51) | SLC6A3SLC6A4ALDH1A1LMNATSHR | |
| SCHEMBL5284224 | 0.85 | ALDH1A1 (0.55) | SLC6A3SLC6A4ALDH1A1LMNATSHR | |
| SCHEMBL3959092 | 0.85 | ALDH1A1 (0.51) | SLC6A3SLC6A4ALDH1A1LMNATSHR | |
| SCHEMBL18539206 | 0.82 | SLC6A3 (0.59) | SLC6A3SLC6A4ALDH1A1LMNATSHR | |
| SCHEMBL5072166 | 0.82 | SLC6A3 (0.59) | SLC6A3SLC6A4ALDH1A1LMNATSHR | |
| SCHEMBL9119782 | 0.81 | TDP1 (0.48) | SLC6A3SLC6A4ALDH1A1LMNATSHR | |
| SCHEMBL22256434 | 0.79 | SLC6A3 (0.65) | SLC6A3SLC6A4ALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5338737-A | Biphenyl oxadiazoles and thiadiazoles as angiotensin II antagonists | WARNER-LAMBERT COMPANY (US) | 1994-08-16 | — | — | US | disclosed |
| US-5210204-A | Hypotensive agents and cardiovascular disorders | WARNER-LAMBERT COMPANY (US) | 1993-05-11 | — | — | US | disclosed |