Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5008126 | 0.81 | KDM4E (0.57) | LMNAALDH1A1HTTMAPTNPSR1 | |
| SCHEMBL9303178 | 0.80 | ALDH1A1 (0.53) | LMNAALDH1A1HTTMAPTGAA | |
| SCHEMBL7276072 | 0.79 | MEN1 (0.49) | LMNAALDH1A1HTTMAPTKMT2A | |
| SCHEMBL7276084 | 0.79 | MEN1 (0.49) | LMNAALDH1A1HTTMAPTKMT2A | |
| SCHEMBL27539557 | 0.78 | ALDH1A1 (0.48) | LMNAALDH1A1HTTMAPTKMT2A | |
| SCHEMBL9303040 | 0.78 | TBXA2R (0.45) | ALDH1A1HTTMAPTGAAKMT2A | |
| SCHEMBL2635654 | 0.77 | ALDH1A1 (0.72) | ALDH1A1HTTGAAKMT2AMEN1 | |
| SCHEMBL2742574 | 0.76 | ALDH1A1 (0.61) | LMNAALDH1A1HTTGAAKMT2A | |
| SCHEMBL9325892 | 0.74 | PTPN1 (0.49) | GAAPOLB | |
| SCHEMBL13215490 | 0.74 | ALDH1A1 (0.43) | ALDH1A1HTTMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5360909-A | THROMBOXANE A2 ANTAGONIST | TERUMO KABUSHIKI KAISHA (JP) | 1994-11-01 | — | — | US | disclosed |
| EP-0562796-A1 | Phenoxyacetic acid compounds and medical preparations containing them | TERUMO KABUSHIKI KAISHA (JP) | 1993-09-29 | — | — | EP | disclosed |