Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.41 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2803737 | 0.95 | ZDHHC7 (0.44) | GPR84FFAR1ZDHHC7MAPTLCK | |
| SCHEMBL260349 | 0.95 | ZDHHC7 (0.44) | GPR84FFAR1ZDHHC7MAPTLCK | |
| SCHEMBL4119282 | 0.93 | ZDHHC7 (0.42) | GPR84FFAR1ZDHHC7MAPTLCK | |
| SCHEMBL7070785 | 0.84 | ZDHHC7 (0.50) | GPR84FFAR1ZDHHC7MAPTLCK | |
| SCHEMBL19690704 | 0.84 | ZDHHC7 (0.50) | GPR84FFAR1ZDHHC7MAPTLCK | |
| SCHEMBL6772533 | 0.83 | GPR84 (0.42) | GPR84FFAR1ZDHHC7MAPTLCK | |
| SCHEMBL13269368 | 0.82 | ZDHHC7 (0.47) | GPR84FFAR1ZDHHC7MAPTLCK | |
| SCHEMBL27958014 | 0.81 | GPR84 (0.50) | GPR84FFAR1ZDHHC7MAPTLCK | |
| Acetic Acid SCHEMBL8675920 | 0.79 | CPB2 (0.53) | GPR84FFAR1ZDHHC7MAPTLCK | |
| Acetic Acid SCHEMBL4741906 | 0.79 | CPB2 (0.53) | GPR84FFAR1ZDHHC7MAPTLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540118-B1 | Photographic material and process | EASTMAN KODAK CO (US) | 1994-12-14 | — | — | EP | disclosed |
| US-5334490-A | Magenta development inhibitor releasing coupler | EASTMAN KODAK COMPANY (US) | 1994-08-02 | — | — | US | disclosed |
| EP-0577210-A1 | A method of preparing a magenta development inhibitor releasing coupler | EASTMAN KODAK COMPANY (US) | 1994-01-05 | — | — | EP | disclosed |
| EP-0540118-A1 | Photographic material and process | EASTMAN KODAK COMPANY (US) | 1993-05-05 | — | — | EP | disclosed |