SCHEMBL260349

SCHEMBL260349

CCCCCCC(C(=O)OCC)C(Cl)Cl

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ZDHHC7 Q9NXF8 1/20 0.44
GPR84 Q9NQS5 7/20 0.41
FFAR1 O14842 1/20 0.41
MAPT P10636 1/20 0.40
CPB2 Q96IY4 1/20 0.40
LCK P06239 1/20 0.40
PPARD Q03181 1/20 0.40
ZDHHC20 Q5W0Z9 1/20 0.40
ZDHHC2 Q9UIJ5 1/20 0.40
FAAH O00519 2/20 0.39
CA2 P00918 1/20 0.39
SMPD1 P17405 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2803737 1.00 ZDHHC7 (0.44) ZDHHC7GPR84FFAR1MAPTCPB2
SCHEMBL4119282 0.98 ZDHHC7 (0.42) ZDHHC7GPR84FFAR1MAPTCPB2
Acetic Acid SCHEMBL9301447 0.95 GPR84 (0.42) ZDHHC7GPR84FFAR1MAPTCPB2
SCHEMBL7070785 0.88 ZDHHC7 (0.50) ZDHHC7GPR84FFAR1MAPTCPB2
SCHEMBL19690704 0.88 ZDHHC7 (0.50) ZDHHC7GPR84FFAR1MAPTCPB2
SCHEMBL6772533 0.88 GPR84 (0.42) ZDHHC7GPR84FFAR1MAPTCPB2
SCHEMBL13269368 0.86 ZDHHC7 (0.47) ZDHHC7GPR84FFAR1MAPTCPB2
SCHEMBL17713606 0.83 ZDHHC7 (0.46) ZDHHC7GPR84FFAR1MAPTCPB2
SCHEMBL2535153 0.81 LMNA (0.45) ZDHHC7GPR84FFAR1MAPTCPB2
SCHEMBL29186605 0.81 GPR84 (0.46) ZDHHC7GPR84FFAR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 283 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118243809-A Method for determining chloronitrobenzene monomer carbon stable isotope and application thereof 广东工业大学 2024-06-25 CN claimed
CN-116621882-A Platinum-based bowl phosphine complex, fullerene array thereof, preparation and application thereof 广西师范大学 2023-08-22 CN claimed
CN-118243809-A Method for determining chloronitrobenzene monomer carbon stable isotope and application thereof 广东工业大学 2024-06-25 CN disclosed
US-RE49918-E1 Cytotoxic benzodiazepine derivatives IMMUNOGEN, INC. (US) 2024-04-16 US disclosed
US-20230346943-A1 SPACER-MEDIATED CONTROL OF UNCAGING PHOTOCAGED MOLECULES THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2023-11-02 US disclosed
CN-116621882-A Platinum-based bowl phosphine complex, fullerene array thereof, preparation and application thereof 广西师范大学 2023-08-22 CN disclosed
CN-115836062-A Compound and medical application thereof 心悦生医股份有限公司 2023-03-21 CN disclosed
CN-114113372-A Method for detecting residual solvent of natural edible pigment 拱北海关技术中心 2022-03-01 CN disclosed
WO-2021150621-A1 SPACER-MEDIATED CONTROL OF UNCAGING PHOTOCAGED MOLECULES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-07-29 WO disclosed
EP-3666289-A1 CYTOTOXIC BENZODIAZEPINE DERIVATIVES ImmunoGen, Inc. (US) 2020-06-17 EP disclosed
US-10647737-B2 Sulfated-glycolipids as adjuvants for vaccines NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2020-05-12 US disclosed
WO-1998002441-A2 NON IMMUNOSUPPRESSIVE ANTIFUNGAL RAPALOGS ARIAD PHARMACEUTICALS, INC. (US) 1998-01-22 WO disclosed
WO-1997026240-A1 CONFORMATIONALLY RESTRICTED AROMATIC INHIBITORS OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN AND METHOD BRISTOL-MYERS SQUIBB COMPANY (US) 1997-07-24 WO disclosed
WO-1997014697-A1 THIENOPYRIDINE DERIVATIVES AS GONADOTROPIN RELEASING HORMONE ANTAGONISTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1997-04-24 WO disclosed
WO-1997009328-A1 PHENYLOXAZOLIDINONES HAVING A C-C BOND TO 4-8 MEMBERED HETEROCYCLIC RINGS PHARMACIA & UPJOHN COMPANY (US) 1997-03-13 WO disclosed
EP-0512352-B1 Substituted carboxylic acid derivatives HOFFMANN LA ROCHE (CH) 1996-03-27 EP disclosed
US-5344843-A Carnitine acryltransferase enzyme inhibitors as antiischemic agents and for cardiovascular disorders HOFFMAN-LA ROCHE INC. (US) 1994-09-06 US disclosed
EP-0512352-A2 Substituted carboxylic acid derivatives F. HOFFMANN-LA ROCHE AG (CH) 1992-11-11 EP disclosed
US-5104883-A Cardiovascular, respiratory, gastrointestirol, urogenital disorders; baldness; premature labor MAY & BAKER LIMITED (GB) 1992-04-14 US disclosed
US-4481144-A 17-Substituted thia-17-alkyl(or alkenyl or alkynyl)androstenes E. R. SQUIBB & SONS, INC. (US) 1984-11-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230346943-A1 SPACER-MEDIATED CONTROL OF UNCAGING PHOTOCAGED MOLECULES DCLRE1A, PCNA, HMBS ZDHHC7 1226/4885GPR84 3340/4885FFAR1 4311/4885
US-10647737-B2 Sulfated-glycolipids as adjuvants for vaccines DEGS1, SGMS1, CD4 ZDHHC7 892/4885GPR84 3243/4885FFAR1 661/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.