Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ADH1B | P00325 | 1/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | ADH4 | P08319 | 1/20 | 0.36 |
| ▸ | ADH7 | P40394 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11348860 | 1.00 | TSHR (0.41) | TSHRALDH1A1TDP1LMNADNM1 | |
| SCHEMBL23673217 | 0.91 | ALDH1A1 (0.45) | TSHRALDH1A1TDP1LMNADNM1 | |
| SCHEMBL10788769 | 0.91 | ALDH1A1 (0.41) | TSHRALDH1A1TDP1LMNACYP3A4 | |
| SCHEMBL7176175 | 0.86 | TSHR (0.41) | TSHRLMNADNM1FAAHTRPV1 | |
| SCHEMBL9784135 | 0.86 | LMNA (0.48) | TSHRLMNADNM1FAAHTRPV1 | |
| SCHEMBL8578514 | 0.85 | LMNA (0.39) | TSHRALDH1A1TDP1LMNACYP3A4 | |
| SCHEMBL10841137 | 0.84 | ALDH1A1 (0.50) | TSHRALDH1A1TDP1LMNADNM1 | |
| SCHEMBL27769610 | 0.83 | LMNA (0.45) | TSHRALDH1A1TDP1LMNADNM1 | |
| SCHEMBL7046403 | 0.80 | ALDH1A1 (0.33) | TSHRALDH1A1TDP1CYP3A4 | |
| SCHEMBL25173853 | 0.80 | TSHR (0.58) | TSHRLMNADNM1FAAHTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354768-A | Use of imidazopyrazole derivatives as analgesics and anti-inflammatory agents | SANKYO COMPANY, LIMITED (JP) | 1994-10-11 | — | — | US | disclosed |