SCHEMBL9301536

SCHEMBL9301536

CN(CCOCCCN)Cc1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 1/20 0.64
PRMT6 Q96LA8 1/20 0.64
PRMT8 Q9NR22 1/20 0.64
TSHR P16473 2/20 0.53
ACHE P22303 4/20 0.51
SIGMAR1 Q99720 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.49
GAA P10253 1/20 0.49
LMNA P02545 1/20 0.49
HTR1D P28221 1/20 0.48
HTR1B P28222 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13909718 0.95 CARM1 (0.62) CARM1PRMT6PRMT8TSHRACHE
SCHEMBL9302526 0.90 CARM1 (0.68) CARM1PRMT6PRMT8TSHRACHE
SCHEMBL2108172 0.83 CARM1 (0.78) CARM1PRMT6PRMT8TSHRACHE
SCHEMBL30380446 0.83 TSHR (0.56) CARM1PRMT6PRMT8TSHRACHE
SCHEMBL30380269 0.83 TSHR (0.56) CARM1PRMT6PRMT8TSHRACHE
SCHEMBL19715501 0.81 TSHR (0.61) CARM1PRMT6PRMT8TSHRACHE
SCHEMBL4604745 0.81 CARM1 (0.75) CARM1PRMT6PRMT8ACHESIGMAR1
Hydrochloric Acid SCHEMBL18730544 0.81 CARM1 (0.75) CARM1PRMT6PRMT8ACHESIGMAR1
SCHEMBL2565534 0.80 SIGMAR1 (0.55) SIGMAR1
SCHEMBL9760037 0.80 TSHR (0.56) CARM1PRMT6PRMT8TSHRACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5288758-A Acetylcholinesterase inhibitors PIERRE FABRE MEDICAMENT (FR) 1994-02-22 US disclosed