Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.62 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.62 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 3/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301536 | 0.95 | CARM1 (0.64) | CARM1PRMT6PRMT8TSHRACHE | |
| SCHEMBL9302526 | 0.89 | CARM1 (0.68) | CARM1PRMT6PRMT8TSHRACHE | |
| SCHEMBL2565534 | 0.85 | SIGMAR1 (0.55) | SIGMAR1 | |
| SCHEMBL4604745 | 0.83 | CARM1 (0.75) | CARM1PRMT6PRMT8ACHESIGMAR1 | |
| Hydrochloric Acid SCHEMBL9373710 | 0.82 | CARM1 (0.72) | CARM1PRMT6PRMT8ACHESIGMAR1 | |
| SCHEMBL8342032 | 0.82 | CARM1 (0.72) | CARM1PRMT6PRMT8ACHESIGMAR1 | |
| SCHEMBL25688953 | 0.82 | CARM1 (0.72) | CARM1PRMT6PRMT8ACHESIGMAR1 | |
| SCHEMBL2108172 | 0.81 | CARM1 (0.78) | CARM1PRMT6PRMT8TSHRACHE | |
| SCHEMBL30380269 | 0.81 | TSHR (0.56) | CARM1PRMT6PRMT8TSHRACHE | |
| SCHEMBL30380446 | 0.81 | TSHR (0.56) | CARM1PRMT6PRMT8TSHRACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090082378-A1 | DERIVATIVES OF 4-(2-AMINO-1-HYDROXIETHYL)PHENOL AS AGONISTS OF THE B2 ADRENERGIC RECEPTOR | LABORATORIOS ALMIRALL, S.A. (ES) | 2009-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090082378-A1 | DERIVATIVES OF 4-(2-AMINO-1-HYDROXIETHYL)PHENOL AS AGONISTS OF THE B2 ADRENERGIC RECEPTOR | ADRB2, ADRA2C, ADRB1 | CARM1 3088/4885PRMT6 2359/4885PRMT8 2767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.