SCHEMBL9304290

SCHEMBL9304290

C=CC(=O)OC(F)(F)C(F)CC

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.37
HPGD P15428 1/20 0.36
ALDH1A1 P00352 5/20 0.35
THRB P10828 2/20 0.34
TP53 P04637 3/20 0.32
HIF1A Q16665 3/20 0.32
CYP3A4 P08684 2/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9301632 0.87 TSHR (0.39) TSHRHPGDALDH1A1THRBTP53
SCHEMBL7753316 0.85 TSHR (0.33) TSHRHPGDTHRB
SCHEMBL9302435 0.83 TSHR (0.46) TSHRHPGDALDH1A1THRBTP53
SCHEMBL63735 0.81 TSHR (0.33) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL10339368 0.80 TSHR (0.41) TSHRHPGDTHRBHSD17B10
SCHEMBL9251422 0.80 TSHR (0.41) TSHRHPGDTHRBHSD17B10
SCHEMBL16105659 0.80
SCHEMBL3132072 0.80 ALDH1A1 (0.35) TSHRALDH1A1TP53HIF1ACYP3A4
Bicarbonate SCHEMBL28045388 0.79 TSHR (0.32) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL28372269 0.79 TSHR (0.32) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118137070-A Modified diaphragm, battery and preparation method of battery 江苏正力新能电池技术有限公司 2024-06-04 CN claimed
US-20150072581-A1 Nanocellulose Composites and Methods for their Preparation and Use EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2015-03-12 US claimed
CN-117645687-B Flexographic printing cold stamping resin, preparation method thereof and alumite coloring layer coating 佛山市三水顺能化工有限公司 2024-08-20 CN disclosed
CN-118137070-A Modified diaphragm, battery and preparation method of battery 江苏正力新能电池技术有限公司 2024-06-04 CN disclosed
CN-117645687-A Flexographic printing cold stamping resin, preparation method thereof and alumite coloring layer coating 佛山市三水顺能化工有限公司 2024-03-05 CN disclosed
WO-2021052071-A1 POLYOLEFIN MATERIAL HAVING POLYMER GRAFTED ON SURFACE, AND PREPARATION METHOD AND APPLICATION THEREOF 浙江伟星新型建材股份有限公司 2021-03-25 WO disclosed
CN-107056999-B Preparation method of fluorine-containing porous material based on amphiphilic fluorine-containing macromolecular block substance stable high internal phase emulsion 济南大学 2020-02-18 CN disclosed
US-20150072581-A1 Nanocellulose Composites and Methods for their Preparation and Use EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2015-03-12 US disclosed
US-5336582-A Electrophotographic image formation comprising an arylamine in a charge transport layer and an encapsulated toner FUJI XEROX CO., LTD. (JP) 1994-08-09 US disclosed
US-5300388-A Toner for electrophotography and process for producing the same FUJI XEROX CO., LTD. (JP) 1994-04-05 US disclosed