Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 13/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 13/20 | 0.64 |
| ▸ | ADRA1B | P35368 | 13/20 | 0.64 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302324 | 0.88 | ADRA1D (0.62) | ADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL9303125 | 0.86 | ADRA1D (0.63) | ADRA1DADRA1AADRA1BCXCR4HTR1A | |
| SCHEMBL9303150 | 0.83 | ADRA1D (0.59) | ADRA1DADRA1AADRA1BCXCR4HTR1A | |
| SCHEMBL9302823 | 0.79 | ADRA1D (0.62) | ADRA1DADRA1AADRA1BCXCR4HTR1A | |
| SCHEMBL9301600 | 0.79 | ADRA1D (0.74) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL9300949 | 0.79 | ADRA1D (0.66) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL7471573 | 0.78 | ADRA1D (1.00) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL13493621 | 0.77 | ADRA1D (0.65) | ADRA1DADRA1AADRA1BPOLBESR2 | |
| Hydrochloric Acid SCHEMBL8124825 | 0.77 | ADRA1D (0.98) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL9302789 | 0.77 | ADRA1D (0.56) | ADRA1DADRA1AADRA1BHTR1APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | claimed |
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | disclosed |