Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 10/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 10/20 | 0.56 |
| ▸ | ADRA1B | P35368 | 10/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303150 | 0.85 | ADRA1D (0.59) | ADRA1DADRA1AADRA1BSIGMAR1ALDH1A1 | |
| SCHEMBL9302823 | 0.85 | ADRA1D (0.62) | ADRA1DADRA1AADRA1BMAPTHTT | |
| SCHEMBL9301600 | 0.83 | ADRA1D (0.74) | ADRA1DADRA1AADRA1BMEN1KMT2A | |
| SCHEMBL9301625 | 0.81 | ADRA1D (0.54) | ADRA1DADRA1AADRA1BMEN1LMNA | |
| SCHEMBL9303125 | 0.80 | ADRA1D (0.63) | ADRA1DADRA1AADRA1BSIGMAR1ALDH1A1 | |
| SCHEMBL9300949 | 0.79 | ADRA1D (0.66) | ADRA1DADRA1AADRA1BPOLBALDH1A1 | |
| SCHEMBL9302324 | 0.78 | ADRA1D (0.62) | ADRA1DADRA1AADRA1BHPGDKMT2A | |
| SCHEMBL9301658 | 0.77 | ADRA1D (0.64) | ADRA1DADRA1AADRA1BPOLBHTR1A | |
| SCHEMBL27536531 | 0.76 | HTR1A (0.54) | ADRA1DADRA1AADRA1BSIGMAR1HTR1A | |
| SCHEMBL9302778 | 0.76 | SIGMAR1 (0.46) | LMNAMAPTKCNH2CACNA1ISIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | claimed |
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | disclosed |