Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 11/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.37 |
| ▸ | BCHE | P06276 | 4/20 | 0.37 |
| ▸ | ACHE | P22303 | 4/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8961860 | 0.89 | KDM4E (0.39) | KDM4EADRB2HTR1ACYP2D6TSHR | |
| SCHEMBL8962096 | 0.86 | KDM4E (0.39) | KDM4EADRB2HTR1ACYP2D6TSHR | |
| SCHEMBL8961888 | 0.84 | KDM4E (0.46) | KDM4EADRB2HTR1ACYP2D6TSHR | |
| SCHEMBL8961922 | 0.82 | ADRA2C (0.41) | KDM4EADRB2HTR1ACYP2D6TSHR | |
| SCHEMBL8961902 | 0.81 | KDM4E (0.46) | KDM4EADRB2HTR1ACYP2D6TSHR | |
| SCHEMBL8961910 | 0.81 | KDM4E (0.41) | KDM4EADRB2HTR1ATP53CYP2D6 | |
| SCHEMBL8962061 | 0.81 | ALDH1A1 (0.42) | KDM4EADRB2HTR1ACYP2D6TSHR | |
| SCHEMBL8962167 | 0.80 | THRB (0.40) | KDM4EADRB2HTR1ACYP2D6TSHR | |
| SCHEMBL8961849 | 0.80 | THRB (0.40) | KDM4EADRB2HTR1ACYP2D6TSHR | |
| SCHEMBL8962339 | 0.80 | THRB (0.40) | KDM4EADRB2HTR1ACYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332431-A | Alkylphenoxy group containing organosilicon compound | NIPPON PAINT CO., LTD. (JP) | 1994-07-26 | — | — | US | disclosed |