Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | EPOR | P19235 | 2/20 | 0.45 |
| ▸ | CCR6 | P51684 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3647251 | 0.82 | ALDH1A1 (0.49) | ABCB1ALDH1A1LMNACTRB1KMT2A | |
| SCHEMBL6904576 | 0.81 | ABCB1 (0.47) | ABCB1ALDH1A1EPORCTRB1TRPM8 | |
| SCHEMBL9330125 | 0.81 | ABCB1 (0.47) | ABCB1ALDH1A1EPORCTRB1TRPM8 | |
| SCHEMBL28454256 | 0.81 | ALDH1A1 (0.44) | ABCB1ALDH1A1CCR6PAX8LMNA | |
| SCHEMBL7994098 | 0.81 | ALDH1A1 (0.50) | ABCB1ALDH1A1CCR6PAX8KMT2A | |
| SCHEMBL1937057 | 0.79 | ABCB1 (0.46) | ABCB1ALDH1A1CTRB1TRPM8ALOX15 | |
| SCHEMBL9737358 | 0.79 | ABCB1 (0.51) | ABCB1ALDH1A1LMNACTRB1KMT2A | |
| SCHEMBL27519798 | 0.78 | ABCB1 (0.53) | ABCB1ALDH1A1LMNAKMT2AMAPK1 | |
| SCHEMBL6705137 | 0.78 | ABCB1 (0.53) | ABCB1ALDH1A1LMNAKMT2AMAPK1 | |
| SCHEMBL17942116 | 0.78 | KMT2A (0.46) | ABCB1ALDH1A1LMNAKMT2ACASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0334236-B1 | Preparation of n-protected alpha-l-aspartyl-l-phenylalanine methyl ester | MITSUI TOATSU CHEMICALS (JP) | 1994-08-31 | — | — | EP | disclosed |
| US-5302743-A | Reacting N-protected L-aspartic anhydride with L-phenylalanine methyl ester salt in non-aqueous solvent | MITSUI TOATSU CHEMICALS, INC. (JP) | 1994-04-12 | — | — | US | disclosed |
| EP-0334236-A2 | Preparation of n-protected alpha-l-aspartyl-l-phenylalanine methyl ester | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-09-27 | — | — | EP | disclosed |