Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27519798 | 0.83 | ABCB1 (0.53) | ABCB1ALDH1A1FOLH1MAPTHPGD | |
| SCHEMBL6705137 | 0.83 | ABCB1 (0.53) | ABCB1ALDH1A1FOLH1MAPTHPGD | |
| SCHEMBL23879154 | 0.82 | ABCB1 (0.52) | ABCB1ALDH1A1FOLH1MAPTHPGD | |
| SCHEMBL30476799 | 0.82 | ABCB1 (0.45) | ABCB1ALDH1A1FOLH1MAPTHPGD | |
| SCHEMBL30476800 | 0.82 | FOLH1 (0.45) | ABCB1ALDH1A1FOLH1CTSLCTSB | |
| SCHEMBL18256433 | 0.80 | ABCB1 (0.54) | ABCB1ALDH1A1SMN1; SMN2L3MBTL1MAOB | |
| SCHEMBL20480994 | 0.80 | ABCB1 (0.54) | ABCB1ALDH1A1SMN1; SMN2L3MBTL1MAOB | |
| SCHEMBL19088636 | 0.80 | ABCB1 (0.54) | ABCB1ALDH1A1SMN1; SMN2L3MBTL1MAOB | |
| SCHEMBL9301690 | 0.79 | ABCB1 (0.49) | ABCB1ALDH1A1LMNACTRB1CASP1 | |
| Benzene SCHEMBL27935192 | 0.79 | ALDH1A1 (0.41) | ABCB1ALDH1A1HPGDCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130307-A | Antibody inhibitors; treating organ graft rejection, fungal infections; antiinflammatory agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-07-14 | — | — | US | disclosed |