Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | GPR174 | Q9BXC1 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302533 | 0.87 | GPR174 (0.67) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9302938 | 0.86 | GPR174 (0.54) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9302948 | 0.86 | GPR174 (0.54) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9847853 | 0.85 | MAPT (0.63) | MAPTALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL9303323 | 0.82 | MAPT (0.54) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9302068 | 0.81 | MAPT (0.63) | MAPTALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL8103160 | 0.81 | MAPT (0.62) | MAPTALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL29847854 | 0.80 | MAPT (0.76) | MAPTALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL16513593 | 0.80 | MAPT (0.76) | MAPTALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL22652069 | 0.79 | MAPT (0.66) | MAPTALDH1A1CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5283248-A | Bactericides, enzyme inhibitor of DNA-gyrase in bacteria | HOFFMANN-LA ROCHE INC. (US) | 1994-02-01 | — | — | US | disclosed |