Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 14/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | GPR174 | Q9BXC1 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301752 | 0.85 | MAPT (0.62) | MAPTCYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL9302948 | 0.83 | GPR174 (0.54) | MAPTCYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL9302938 | 0.83 | GPR174 (0.54) | MAPTCYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL9302533 | 0.82 | GPR174 (0.67) | MAPTCYP1A2CYP2C9CYP2C19GAA | |
| SCHEMBL521692 | 0.80 | MAPT (0.76) | MAPTCYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL29525723 | 0.78 | MAPT (0.56) | MAPTCYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL17896593 | 0.78 | MAPT (0.56) | MAPTCYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL9303323 | 0.78 | MAPT (0.54) | MAPTCYP1A2CYP2C9CYP2C19GAA | |
| SCHEMBL8657225 | 0.78 | MAPT (0.51) | MAPTCYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL7546017 | 0.77 | MAPT (0.71) | MAPTCYP1A2CYP2C9CYP2C19GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430847-A1 | Procedure for the preparation of N-cyclopropyl-4-fluoroanilines | CENTRO MARGA PARA LA INVESTIGACION S.A. (ES) | 1991-06-05 | — | — | EP | disclosed |